I second Frank's comments about FTDI chips. They are about as bullet proof as
you will find.
One of the reasons for problems with the Prolific chips is that they are widely
cloned. Prolific
started adding code to their drivers to identify cloned units, and not work
with them even though the
Scott,
Frank, K4FEG here, I do not know if this would applicable to your
situation, but while I was having control issues with my Icom Ic-910H
and SatPC32, I reached out to Erich (writer of SatPC32) about the issues
and he told me that some of the cables and other interface modules
(USB/Serial