Hi Anbarasu.
Comments below.
Hi Mark,
Thanks for your suggestions. What I have tried so far is: I removed all
outliers CEL files from rawData and re-run the analysis. I was expecting
a
slightly different intensity distributions of chips (due to quantile
normalization) but it seems I have
Hi Yiwen.
I think this thread will answer your question in detail:
http://groups.google.com/group/aroma-affymetrix/browse_thread/thread/1b0ab11fad9b4df3
In brief, the main difference is how the probe-level linear model is fit
-- median polish OR iteratively reweighted least squares with a