*PhD Position: Structural biology of protein-protein interactions in the
muscle Z-disk*
We are seeking a highly motivated PhD student to work on structural
characterization of important protein complexes centered on major
players of the Z-disk of striated muscle: alpha-actinin and filamin.
although I agree with the statement below, I would say that X-ray
crystallography also only generates a molecular model (not a
structure). Rather than a structure, X-ray crystallography generates
an electron density map. The quality of the model based in it depends
on the quality of this
I have questions about baubles in general. I find that using firefox
(3.0.4 windows) baubles logs do not open directly from ccp4i or imosflm
and I get an error i is not a registered protocol (or c) which I think
is the drive the file is on. However if I open the file in via open
file then it
Google chrome works perfect for this
regards
spyros
O/H Nicholas Keep ??:
I have questions about baubles in general. I find that using firefox
(3.0.4 windows) baubles logs do not open directly from ccp4i or imosflm
and I get an error i is not a registered protocol (or c) which I think
is
Dear Tassos, Bernhard and David,
If I may push this humourous response (obviously tainted with
crystallographic bias) a little further, I would say that my favourite
mnemonic for the acronym NMR is
N eeds
M ore
I think we should slowly arrive in the 21st century and realize that
methods are complementary to each other.
I've never done NMR by myself only some xray stuff and attempts to
merge EM data with xray almost 10 years ago to arrive at ab initio
phases.
Sure one can argue what information can
How about this one:
Can't
Refine
Your
Structure
To
Acceptable
Likelihood
Typical error bars on crystallographic data are ~5% (R_sym), but with
very few exceptions the models in the PDB do not fit their corresponding
observations to better than ~40% error (R_cryst for intensities).
Gerard?
