As famously observed by the Yes Minister teamthe dream outcome for any
organization:
http://www.youtube.com/watch?v=x-5zEb1oS9A&feature=youtube_gdata_player
J
Sent from my iPhone
On 07/04/2012, at 3:16 AM, Patrick Loll wrote:
> Ron makes an excellent point. Many institutions devote far mo
I wouldn't recommend this option
Phil
On 6 Apr 2012, at 21:41, Matthew Chu wrote:
> Hi all,
>
> Can someone kindly explain what is that "match pairs related by inversion of
> indices" option doing for handling anomalous data? If I have collected the
> inverse beam data, does it mean I have to
Hi all,
Can someone kindly explain what is that "match pairs related by inversion
of indices" option doing for handling anomalous data? If I have collected
the inverse beam data, does it mean I have to use this option to match the
I+ and I- pairs in merging? But why does it lead to seriously incom
Do run the data through Pointless before Scala to check the point group.
Try "scales constant" just to check that things aren't completely hopeless
Phil
On 6 Apr 2012, at 20:29, Yuri Pompeu wrote:
> Hi everyone,
> Sorry for the newbie type problems, but I am just starting to use ccp4 for
> dat
There are two immediate openings for protein crystallographer position in
Harvard Medical School. One of the research projects is focused on the
structural and functional investigation of Wnt signaling pathway. The
project is the close collaborative efforts between Professor Xi Hes lab
at Children
One quick thought is - are you trying to scale reflections that don't really
exist? I.e are you trying to push your resolution a bit too much?
Tony.
Sent from my iPhone
On 6 Apr 2012, at 20:29, "Yuri Pompeu" wrote:
> Hi everyone,
> Sorry for the newbie type problems, but I am just starting
Hi everyone,
Sorry for the newbie type problems, but I am just starting to use ccp4 for data
processing.
Here is my problem.
After I index and integrate my images using iMOSFLM, I end up with the .mtz
files that contains, AIUI, unmerged reflections.
Next I should try to merge and scale experiment
In response to very welcomed suggestions from the bb, we have opened the
hiring of this position to include non-Ph.D. candidates. Please see the
updated posting below:
Enquires and applications (coverletter and C.V) can be forwarded to
j...@microlytic.com. The posting is also available at
www.mi
Ron makes an excellent point. Many institutions devote far more energy to
limiting risk than to doing the right thing. This leads administrators to a
frightening, but logical conclusion: The less science we do, the less chance of
our doing something that could invite a penalty on the university.
Dear John,
Your points are well taken and they're consistent with policies and practices
in the US as well.
I wonder about the nature of the employer's responsibility though. I sit on
some university committees, and the impression I get is that much of the time,
the employers are interested
*This posting is also available at *http://www.microlytic.com/careers .
*
*
*Please submit a coverletter and C.V. to supp...@microlytic.com. **All
general enquiries may be also be directed to this address.*
*
*
*Position Summary:*
Your primary focus will be the commercialization of Microlytic
If you have a DLS you can try playing with different [NaCl] or pH and see if
you can push the equilibrium in one direction.
Jürgen
On Apr 6, 2012, at 11:41 AM, 杨贝 wrote:
Dear All,
I have a 100KD protein which elutes as a mixture of 90% monomer and 10% dimer
on HPLC, if I pool the monomer frac
Dear All,
I have a 100KD protein which elutes as a mixture of 90% monomer and 10%
dimer on HPLC, if I pool the monomer fractions and reload them onto the
column, the elution profile is still 90% monomer plus 10% dimer, and the
same is true if I do so to the dimer peak. Collectively, there seems
I don't see how a self rotation function can determine SG. If you processed
data as P1 then found the SR maps showed 3 folds and 2 folds you might
suspect that POINT GROUP!!! (Remember space groups are guessed on the basis
of systematic absences - you don't really know that till you have a
stru
You know that point group has two indexing conventions (h k l and -k,-h,-l
if I remember - see the CCP4 documentation on alternate indexing and use
pointless to sort it out.. Eleanor
. Use pointless to check On Apr 4 2012, Deepthi wrote:
Hello everyone
I have a problem scaling the MAD data wh
This could well be due to radiation damage - S are often affected, also Glu
and Asp side chains. It is hard to know what to do since the effects are
time related. If you have high redundancy maybe you could not use he later
batches? Otherwise maybe just relax the B factor restraints and let them
Dear Ron,
Re (3):-
Yes of course the investigator has that responsibility.
The additional point I would make is that the employer has a share in
that responsibility. Indeed in such cases the employer university
convenes a research fraud investigating committee to form the final
judgement on continu
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