Dear All,
The Grenoble Outstation of the European Molecular Biology Laboratory
is seeking to recruit a Group Leader in Structural Biology of Complexes.
The appointed Group Leader will be an ambitious structural biologist
with an original multidisciplinary research programme oriented towards
Dear all,
I24 is the microfocus MX beamline at Diamond offering a fully tuneable and
versatile X-ray beam for some of the most challenging crystals in structural
biology. There currently an opportunity to join I24 as a beamline scientist
during an exciting period of significant upgrades and cha
Gloria,
Here is how we are now doing it, courtesy of Yu-Jing's and Merlin's fine
development work. We have also tried it to quantitatively remove tags by TEV
cleavage, but we haven't solved that problem yet.
Regards,
Michael
Tan, Yu-Jing, Wei-Han Wang, Yi Zheng, Jinlan Dong, Giovanni Stefano
Resonance was to be understood exactly as meaning all the bonds are
averaged between both types (single and double bonds).
Furthermore, fluctuations in the immediate environment will affect
electron distribution with time, as proteins exist in a dynamic state.
Nadir Mrabet
Pr. Nadir T. Mrabet
The Phenix developers are pleased to announce that version 1.8.4 of Phenix is
now available. Binary installers for Linux, Mac OSX, and Windows platforms are
available at the download site:
http://phenix-online.org/download/
Highlights from this version:
Automated MR/ligand fitting/refi
John Bohannon wrote about his experience writing "a computer program to
generate hundreds of unique papers." Thought some of you might find it of
interest:
John Bohannon. Who's Afraid of Peer Review? Science 342 (Oct. 4, 2013) 60-65.
DOI: 10.1126/science.342.6154.60
http://www.sciencemag.org/con
Hi Navdeep,
I feel disappointed. (not your fault)
I was hoping to see what kind of science was behind the computer program
that generated the unique papers. That doesn't seem to be contained in the
linked article.
The article does, however, seem to be lacking in peer review itself? Or can
anythi
2013/10/9 Folmer Fredslund
> Hi Navdeep,
>
> I feel disappointed. (not your fault)
>
> I was hoping to see what kind of science was behind the computer program
> that generated the unique papers. That doesn't seem to be contained in the
> linked article.
>
> The article does, however, seem to be
Hi all,
Thank you guys so much for the useful suggestions. I could fit the ligand
to electron density by doing the following:
1. Run Phenix. eLBOW by loading the smile string and generate the pdb file
and cif file.
2. Import CIF dictionary and open pdb for the ligand generated in
Phenix.eLBOW and p
Sorry for a provocative question, but I am surprised why nobody
comments/congratulations laureates with regard to recently awarded Nobel
prizes? However, one of laureates in chemistry contributed to a popular method
in computational crystallography.
CHARMM -> XPLOR -> CNS -> PHENIX->…
Alex Al
Perhaps because the (macromolecular) crystallography community is becoming a
bit blase about Nobel prizes being awarded to one or several of its
distinguished colleagues almost every year?
(Ok, not quite).
Klaus
===
Dr. Kl
Good point. Now since you mentioned contributions of the recent Nobel laureates to crystallography Mike Levitt also had a significant contribution through the by now forgotten Jack-Levitt refinement which to the best of my knowledge was the first time
that x-ray term was added to the energy min
Levitt also contributed to DEN refinement (Schroder et al. 2007, 2010).
-Nat
On Wed, Oct 9, 2013 at 2:29 PM, Boaz Shaanan wrote:
> Good point. Now since you mentioned contributions of the recent Nobel
> laureates to crystallography Mike Levitt also had a significant
> contribution through the
It deserves comment!! I've been too busy talking with my friends about it to
think of CCP4.
This morning on NPR I heard Karplus's name and started to whoop and holler, and
by the time they got to Arieh I realized they had a Hat Trick!! It's a
spectacular thing that this field should get recog
Hi denizens,
Now that Biology has gone missing, at least in the programs of the
funding agencies in this part of the world, the reflections that I'm
going to expose concern at best that even smaller field of natural
philosophy that we euphemistically call, not without a twist of candour,
"biomedic
Hi scientists,
this interesting topic brought back to my mind a similar discussion I had with
a colleague of mine and now I want to share it with you guys.
As Vale already pointed out, the peer-review process seems to be far from an
ideal system: there are many papers in which one of the author i
Hi Marco,
Impact factor is the last refuge of the publishing system as it is.
Precisely because in this ocean of untrusted publications we tend to
believe that high impact factor journals deserve our respect. This is
more or less all right: among those who have investigated the issue some
are more
(Sorry if you get this twice. The first time as marked as junk by our
email server. Well, it may be junk after all...)
Hi Marco,
Impact factor is the last refuge of the publishing system as it is.
Precisely because in this ocean of untrusted publications we tend to
believe that high impact fact
Even if you remove the authors it is often easy to ascertain who they are by
reading the paper and reference list.
Marco Lolicato wrote:
>Hi scientists,
>this interesting topic brought back to my mind a similar discussion I had with
>a colleague of mine and now I want to share it with you guy
Many (more) reviewers - [panic on Roberto's face]
Isn't real peer-review just a question of standing the test of time?
A piece of work blatantly wrong will sooner or later be picked up by someone
(although I acknowledge that wrong papers can have serious consequences on
one's ability to
g
And just to add a little further to Mark's point, is there anyone here who
has at some stage received reviewer comments and NOT immediately spent the
next little while trying to deduce who each of the reviewers were?
(especially if they were negative...)
I would imagine most people have a pretty g
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