Fyi
*
Academic Coordinator in the Biophysics Team
Presentation of the Center
The Novo Nordisk Foundation Center for Protein Research (CPR --
www.cpr.ku.dk) at the Faculty of Health Sciences, University of
Copenhagen, performs basic and applied discovery research on human
Dear all,
The EMDB team at the Protein Data Bank in Europe (PDBe; http://pdbe.org) has
two vacancies for scientific programmers to work on an exciting new MRC and
BBSRC funded project to help bridge the worlds of cellular and molecular
structural biology. The project aims to develop:
1) a
Is n't the danger here that you are just fitting to noise generated by the rest
of the Unit Cell that you are ignoring. So it is easy to do a 'good bit' of
modelling in a specific region. Just like some tennis players have very good
serves but do not win matches.
Dear Colleagues,
This is a reminder that applications are still open forBIOCRYS 2014
Fundamentals of Modern Methods in Biocrystallography
organised by Maria Armenia Carrondo and Thomas R. Schneider. Closing
date for applications is the 15th July.
*Course sponsored by :* FEBS, BioStruct-X and
Hi,
I was looking at the Kleywegt et al paper from 2004 'The Uppsala Electron
Density Sever'
and I was trying to follow the steps outlined in the paper (section 3)
'Generating the maps'
I found RAVE/DATAMAN on the Uppsala s/w factory but for my OS X (10.7.5) it
seems it is no longer supported.
The Liao laboratory at Harvard Medical School (Department of Cell
Biology) has an opening for a postdoctoral scientist.
Our laboratory uses high-resolution single-particle electron
cryo-microscopy (cryo-EM) to study the structure and function of
membrane proteins. We seek a highly motivated
I got the answer for this question from Gerard Kleywegt himself, I thought
I will post it here in case it is useful for anyone else.
http://xray.bmc.uu.se/markh/usf/
Thank you Todd for pointing me to Bill Scott's page, it is a useful
resource to know.
On Thu, Jun 12, 2014 at 11:40 AM,
Hello folks can u please help me by telling that where can i avail SAXS
facility??
and Cryo EM too??
Regards
Ruby
Hi, Tim,
Thanks for your comment. Do you agree with the editorial's claim that some 25%
of the deposited protein-ligand complexes might be dodgy in significant
details?
This editorial comment represents something that I often hear from drug
discovery professionals. Is it a matter of PR
What part of the world are you in?
Kushol
Kushol Gupta, Ph.D.
Research Associate - Van Duyne Group
Department of Biochemistry and Biophysics
Perelman School of Medicine at The University of Pennsylvania
mailto:kgu...@upenn.edu kgu...@upenn.edu / 215.573.7260 / 267.259.0082 /
Hi Jeff,
there are quite a few implications in your brief email that each might
open a long thread of discussion. As brief as possible I think one has
to be a good scientist and a good crystallographier to fully understand
the meaning of a crystal structure, and I think many people believe a
Dear Ruby,
Most synchrotrons will have a beamline designed for small angle solutions
scattering. It would depend on your geographical location, which facility you
may prefer to look at. Their websites have detailed information about what
beamlines are available to external users and what type
Hello All,
I have tried MR in Phaser, MRage, Molrep , Mrbump but i
am not getting the true solution which it supposed to be. Although the
resoution of data is 6.1A, but i want to give a try to CNS and see if I can
find right solution. I have read the manual of CNS but i am
Hi,
I saw Jeffs post with interest and have held off until now. It is relatively
easy to find structures with bad geometry for small molecules but it does not
do any good simply pointing them out. What I believe is needed is a way to fix
the problem. There are several possible ways. The pdb
On Thursday, 12 June, 2014 20:24:43 Joel Tyndall wrote:
Hi,
I saw Jeffs post with interest and have held off until now. It is relatively
easy to find structures with bad geometry for small molecules but it does not
do any good simply pointing them out. What I believe is needed is a way to
Great news and I am in full support of the bug option. Where do we start?
(Caveat: we all make mistakes, I am sure I have!)
-Original Message-
From: Ethan A Merritt [mailto:merr...@u.washington.edu]
Sent: Friday, 13 June 2014 8:45 a.m.
To: Joel Tyndall
Cc: CCP4BB@jiscmail.ac.uk
Subject:
Earlier this year for the first time I got back a validation report from the
PDB for a deposited structure that included wwPDB validation of a ligand.
This is great stuff. I approve. I am happy.
Unfortunately the validation check reported problems with my ligand.
This is bad. I am unhappy. What
On 13/06/14 00:19, Ethan A Merritt wrote:
Earlier this year for the first time I got back a validation report from the
PDB for a deposited structure that included wwPDB validation of a ligand.
This is great stuff. I approve. I am happy.
Unfortunately the validation check reported problems with
Applications are invited for a postdoctoral position at Washington University in St. Louis. The NIH supported research will focus on the structure and function of intramembrane enzymes.
Studies will use multidisciplinary approaches including macromolecular X-ray crystallography, biochemistry,
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