Re: [ccp4bb] Nitril groups not present on compounds

2019-02-26 Thread Holton, James M
10% of which beam? -James Holton MAD Scientist On Feb 26, 2019, at 1:38 PM, Maria Håkansson mailto:maria.hakans...@saromics.com>> wrote: Dear all, We have experienced nitril groups not present in the electron density after data collection on compounds bound to different proteins. In one of

Re: [ccp4bb] Nitril groups not present on compounds

2019-02-26 Thread Mark J van Raaij
Hi Maria, from the picture, it looks like disorder to me. Note that the three non-H atoms at the top of the ring also have significantly less density than the five non-H atoms that are closer to the protein. Perhaps the compounds is just quite wobbly in it's binding site. Mark J van Raaij

[ccp4bb] Postdoctoral position in structural biology of influenza virus transcription Cusack group, EMBL Grenoble

2019-02-26 Thread Stephen Cusack
Dear All,     We are looking for a highly motivated and ambitious individual to progress our understanding of the mechanism of transcription by influenza virus RNA-dependent RNA polymerase. The work is in the frame of the ANR-funded FluTranscript project that brings together the

[ccp4bb] CSMB Postdoctoral Research Associate, Oak Ridge National Laboratory

2019-02-26 Thread O'Neill, Hugh
Postdoctoral Research Associate at the Center for Structural Molecular Biology, Oak Ridge National Laboratory The Center for Structural Molecular Biology (CSMB) has a postdoctoral fellow position available to work in the area of structural biology/experimental biophysics. In this position, you

[ccp4bb] Reminder: Call for MX beamtime proposals at HZB, BESSY II, deadline March 01, 2019

2019-02-26 Thread Manfred S. Weiss
Dear all, I would just like to remind you of the upcoming deadline. Best wishes Manfred, on behalf of the HZB-MX team the next MX-proposal application deadline: March 01, 2019 is approaching https://www.helmholtz-berlin.de/user/beamtime/proposals/index_en.html As usual, all proposals will