[ccp4bb] Postdoc opportunity

2019-12-10 Thread Elias Lolis
A postdoctoral associate position is available in the lab Prof. Elias Lolis at the Department of Pharmacology, Yale University, to work on the structures of chemokine receptor (GPCR) complexes. The chemokine and chemokine receptors function as homeostatic and/or inflammatory proteins and are

Re: [ccp4bb] Examples of EM models at 4.0Å or better with serious modelling errors?

2019-12-10 Thread Pavel Afonine
Dear Gerard, a possible programmatic approach may be a loop over all (model, map, resolution) or (model, map, half_map1, half_map2, resolution) from PDB/EMDB and calling phenix.validation_cryoem model. emdb_.map resolution=value > .log or phenix.validation_cryoem model. emdb_.map

Re: [ccp4bb] Cysteine sulfenic acid in coot

2019-12-10 Thread Petri Kursula
I used to always do this in a text editor - old-fashioned by fast and works :) Petri Petri Kursula -- Professor -- Department of Biomedicine University of Bergen, Norway http://www.uib.no/en/rg/petrikursula petri.kurs...@uib.no -- Faculty of Biochemistry and Molecular

Re: [ccp4bb] Cysteine sulfenic acid in coot

2019-12-10 Thread Lumbini Yadav
Sudipta to link this amino acid you have to renumber the residues before and after the modified position where residue is added such that it accepts the residues as part of chain. Also you should give similar chain id to modified residue, as the chain in which you want to merge Hope this helps.

Re: [ccp4bb] Cysteine sulfenic acid in coot

2019-12-10 Thread Paul Emsley
On 10/12/2019 15:11, Sudipta Bhattacharyya wrote: > Dear community, > > I would really appreciate your suggestions for linking cysteine > sulfenic acid (one of the active site amino acid residues in my target > protein) to rest of the protein chain. Let me summarize what I did so > far in coot  -

[ccp4bb] Cysteine sulfenic acid in coot

2019-12-10 Thread Sudipta Bhattacharyya
Dear community, I would really appreciate your suggestions for linking cysteine sulfenic acid (one of the active site amino acid residues in my target protein) to rest of the protein chain. Let me summarize what I did so far in coot - 1. I deleted the native cysteine residue at that location,

[ccp4bb] Examples of EM models at 4.0Å or better with serious modelling errors?

2019-12-10 Thread Gerard DVD Kleywegt
Dear colleagues, We are developing a new validation method that takes EM maps and models into account. In order to understand the potential, the applicability and the limitations of the method we are looking for good test cases, which turn out to be surprisingly hard to find. What we are

[ccp4bb] Understanding Biology through Structure, March 16-20 2020, Santa Fe, NM

2019-12-10 Thread Tom Terwilliger
Hi Structural Biology colleagues! A few student/postdoc fellowships are still available for Understanding Biology through Structure 2020 (https://cvent.me/4kq9P March 16-20, 2020 in Santa Fe, NM). The conference is a forum where students and postdocs can meet established researchers and discuss