[ccp4bb] Autodock4Zn

Dear all, I know that this may be a bit off topic, but I nonetheless hope that I can get some help, as I had problems to reach the Autodock mailing list. I am using the software Autodock and Autogrid on a Linux system. I would like to use Autodock4Zn forcefield for docking. Unfortunately, th

[ccp4bb] Senior scientist crystallographer position at Evotec

Dear CCP4 community, We currently have a crystallographer position open in our structural biology team. If you are interested, please apply using this link: https://evotecgroup.wd3.myworkdayjobs.com/Evotec_Career_Site/job/Abingdon/Crystallography-Senior-Scientist_REQ-03307 Best wishes, Stephani

[ccp4bb] Deadline today -- IUCr SARS-CoV-2 special symposia.

Dear BB, As you might be aware, there are a few microsymposia that have been added to this year’s IUCr conference on developments around SARS-CoV-2. Given the wide interests of this board, I wanted to advertise all four of the sessions, for which the (official) deadline is TODAY: - Structural

[ccp4bb] CCPBioSim Industry Seminar 2 June 2021

Dear all, Our next industry seminar is on 2 June 2021 at 15:00 BST (registration deadline Monday 31 May 2021). Please join us to hear Silvia Lovera from UBC BioPharma talking about adaptive sampling for molecular dynamics and applications to drug binding. All the details and the free registrat

[ccp4bb] Cryo-EM data processing specialist at the Hauptman-Woodward Medical Research Institute

To anyone who may be interested, please see the application instructions below. The search is open but will close soon. The Cryo-EM Center at the Hauptman-Woodward Medical Research Institute (HWI) seeks a scientist to enrich its scientific activities. The newly-built Center is purposefully gear

[ccp4bb] me7G-pp- mRNA 5' cap dictionary

Can anyone tell me where to find a model dictionary entry for COOT and/or phenix for the 7meG-pp residue that forms the 5’ cap on a messenger RNA ? I need to be able to bond it to the 5’-end of an RNA model and bond it to the existing 5’-phosphate of the first ribonucleotide. Thanks, Laurence

Re: [ccp4bb] me7G-pp- mRNA 5' cap dictionary

Yes but without the methyl groups on the sugars. I scavenged a GTA capped RNA from a PDB - 5wfh - which draws the link from the GTA to the 5’-phosphate of the RNA, but when you regularise them in coot, it breaks the connecting bond. However after just starting to reply to you I realised that the

[ccp4bb] Post Position at AbbVie (Chicago, IL, USA): CFTR Structural and Function Studies

Dear Colleagues, I am writing to let you know that AbbVie’s Cystic Fibrosis Biology Group is currently looking for a Post-doctoral researcher to study structural and functional properties of Cystic Fibrosis Transmembrane Receptor (CFTR) protein using Cryo-EM and cellular functional assays. The goa

[ccp4bb] Membrane proteins- Postdoc opportunity at Umeå University

Hi all, If you are interested in membrane proteins + structural biology please apply for this fellowship! We are looking for someone with a solid background in structural biology (crystallography and/or EM) and biophysics/biochemistry. Previous work with membrane proteins is highly desirable! Qu

[ccp4bb] Molecular Glues/ Targeted Protein Degradation Postdoc position

Hi, We are recruiting a driven postdoc to support the structural biology aspects of our highly collaborative project on targeting transcription factor drivers in childhood cancer using molecular glues in the hot field of targeted protein degradation. The position is available *immediately* and fu

[ccp4bb] postdoc position in structural biology

Dear Colleagues, A postdoctoral position is immediately available for a highly motivated individual interested in understanding molecular mechanisms of ubiquitin signaling. Research is focused on the enzymatic machinery responsible for protein ubiquitination, characterization of PROTAC complex