[ccp4bb] Second NYC Integrative Structural Biology symposium (NYC-ISB24) - Oct 9-11, 2024 - NYC, USA

Dear all, General registration is now open for NYC-ISB24: http://nyc-isb24.eventbrite.com This 3-day event will be held October 9-11, 2024 at CUNY ASRC and NYSBC, and is focused on integrative

[ccp4bb] Postdoc position Sweden

Hi, We’re looking for a postdoc at Umeå University to work on membrane protein structural biology with a variety of methods, such as cryo-EM and X-ray solution scattering. The project can be accommodated to fit the interests of the candidate. This is a great opportunity to contribute to

Re: [ccp4bb] Experimental phasing Selenomethionine data collection etc. tips

I agree with Harry, I suspect that embarrassment has no definition/ meaning in the context of Nature. From: CCP4 bulletin board on behalf of Harry Powell <193323b1e616-dmarc-requ...@jiscmail.ac.uk> Sent: Tuesday, May 14, 2024 6:28 PM To:

Re: [ccp4bb] Experimental phasing Selenomethionine data collection etc. tips

Hi Marco, An alternative would be to scrap the SeMet crystals and collect anomalous data on native crystals at I23, Diamond Light Source. We are optimised for S-SAD and could likely help you with your phasing. Happy to talk off-list if you'd like to come and do an experiment (I am a beamline

Re: [ccp4bb] AlphaFold3 Transparency and Reproducibility

Do Nature do embarrassment? H > On 14 May 2024, at 10:54, Frank von Delft > wrote: > > What we really need is a tweet from Nature, declaring their embarrassment at > having been suckered into becoming DeepMind's advertising arm. > > > On

Re: [ccp4bb] AlphaFold3 Transparency and Reproducibility

What we really need is a tweet from Nature, declaring their embarrassment at having been suckered into becoming DeepMind's advertising arm. On 14/05/2024 01:56, Paul Adams wrote: The letter may have had (or helped have) an impact already: On X today from Pushmeet Kohli @ DeepMind "We love

Re: [ccp4bb] Experimental phasing Selenomethionine data collection etc. tips

Hi With this in mind, I have found the easiest way to generate AlphaFold models (for those not in the DB) is actually in CCP4 Cloud-remote - makes MR using AF models a real doddle. See the Tutorials (in particular on MR) available with CCP4 Cloud. Harry > On 14 May 2024, at 09:20, Randy

Re: [ccp4bb] Experimental phasing Selenomethionine data collection etc. tips

Dear Marco, You don’t mention here or in the earlier thread whether you tried AlphaFold models and, if you did, how you prepared them for MR. I’m happy to hear of any case where we still need experimental phasing methods to solve new protein structures, but we’ve seen very few examples where

[ccp4bb] PDRA in serial crystallography at Diamond Light Source

Hi all, We have a PDRA position open at Diamond to help us develop new methods for time-resolved crystallography. You will work closely with a number of groups at Diamond and beyond to improve approaches for both SSX and SFX. For further info and to apply see