[ccp4bb] postgraduate studentship available

2011-06-23 Thread Jim Spencer, Cellular and Molecular Medicine
Dear ccp4bb, Apologies for the off-topic posting, but I would be grateful if you could bring the availability of the PhD studentship detailed below to anyone who may be interested. Funding restrictions dictate that the position is open to EU nationals who are normally domiciled in the UK.

[ccp4bb] (off topic) effective chemical lysis of E. coli under anaerobic conditions

2011-11-29 Thread Jim Spencer, Cellular and Molecular Medicine
Dear All, Apologies for the off-topic question. I'm seeking suggestions on the best way to achieve an effective, but not over-harsh, chemical lysis of E coli expressing an oxygen-sensitive Fe-S protein. We need to lyse anaerobically but do not have access to a sonicator that we can use in th

[ccp4bb] postdoctoral position on radical-SAM Fe-S protein

2011-02-15 Thread Jim Spencer, Cellular and Molecular Medicine
Dear All, A postdoctoral position is available in my laboratory (University of Bristol, Medical Sciences Building) to continue our characterisation of the radical SAM enzyme Cfr, an Fe-S-containing rRNA methyltransferase that confers resistance to multiple classes of ribosome-acting antibiotic

[ccp4bb] Post-doctoral position available

2012-06-15 Thread Jim Spencer, Cellular and Molecular Medicine
Dear All, A postdoctoral position is available in my lab to study the interactions of zinc-dependent (metallo) beta-lactamases with beta-lactam substrates and candidate inhibitors using both rapid kinetics and X-ray crystallography. The position will be offered for one year in the first instan

[ccp4bb] postdoctoral position at the University of Bristol

2008-09-24 Thread Jim Spencer, Cellular and Molecular Medicine
Dear All, A one year postdoctoral position is available immediately in the lab of Dr. Jim Spencer in the Department of Cellular and Molecular Medicine at the University of Bristol, U.K. The successful applicant will work to biochemically characterise and crystallise a novel metalloprotein inv