Francis,
One common response is "try a number of different B-factor refinement
> protocols, use Rfree as a guide to determine which one is appropriate".
I recognize my advice along those lines above -:)
Although now I would say (assuming phenix.refine): "Try individual
ADP refinement first, and
On Fri, 2012-01-06 at 11:18 -0700, Francis E Reyes wrote:
> I've seen the following question asked: At what resolution is
> (individual,group,one per residue, two per residue,overall)
> appropriate?
My personal opinion is that the individual B-factor refinement with
restraints proper to the resol
Pete brings out two concerns: [1] B-factor refinement being stable, [2]
over-fitting at low resolutions. Here I'll suggest low resolution to be in the
3-4A range.
I've seen the following question asked: At what resolution is
(individual,group,one per residue, two per residue,overall) appropr
