Hi Jonathan,
This is purely a chemistry guess, but if you have a PEG400 derived compound
like:
(HO)-CH2-CH2-O-CH2-CHO,
i.e, part oxidised, then the CHO might form a N,O acetal ring with the free
amine and side chain. Five membered ring formation is kinetically
favourable, though the chemistry mi
Dear bb,
I have a high resolution dataset showing that the N-terminal threonine
of my protein has been modified and cyclized, with the main chain N and
side chain OG1 now involved in a non-planar 5 membered ring sugar-like
structure. The molecule seems to be 5-6 atoms long with some 'head grou
