Re: [Freesurfer] Mean diffusivity on cortex?

2017-08-21 Thread Douglas N Greve
The data in gtm.nii.gz is in floating point. If you want to change the gtm.stats file, you'll have to rescale the input, eg, fscalc input.nii.gz mul 1000 -o input-time-1000.nii.gz On 08/15/2017 04:09 AM, Shane Schofield wrote: > Hello Dr Greve, > > I have ran the command and got the data from t

Re: [Freesurfer] Mean diffusivity on cortex?

2017-08-17 Thread Douglas N Greve
Sorry, I don't know if that info is in PET dicom files On 08/16/2017 07:14 PM, Shane Schofield wrote: > Okay I understand. > > So I ideally would like to do the PetSurfer before actually working > on the BPND but I already got them in the BPND format as well as the > raw dynamic images. I trie

Re: [Freesurfer] Mean diffusivity on cortex?

2017-08-16 Thread Shane Schofield
Okay I understand. So  I ideally would like to do the PetSurfer before actually working on the BPND but I already got them in the BPND format as well as the raw dynamic images. I tried to obtain the BPND data out from PetSurfer myself, but then I realise I don't any time.dat with me.mri_glmfit

Re: [Freesurfer] Mean diffusivity on cortex?

2017-08-16 Thread Douglas N Greve
SUVR you can. BP is a little trickier because BP estimation is a nonlinear operation that can be biased by noise. Probably it comes out similarly. On 08/16/2017 02:50 PM, Shane Schofield wrote: > Hi Dr Greve, > > On a similar note, can I use the Petsurfer on PET data that have > already been a

Re: [Freesurfer] Mean diffusivity on cortex?

2017-08-16 Thread Shane Schofield
Hi Dr Greve, On a similar note, can I use the Petsurfer on PET data that have already been averaged into a single frame 3D volume instead of 4D? Example, SUVR and BPND data. Thanks for your help again. On Tuesday, August 15, 2017, 9:09:33 AM GMT+1, Shane Schofield wrote: Hello Dr Greve, I hav

Re: [Freesurfer] Mean diffusivity on cortex?

2017-08-15 Thread Shane Schofield
Hello Dr Greve, I have ran the command and got the data from the gtm.stats.dat. However, all the values are 0.001 - 0.003. Can I scale it up or show the data with more precision? Thank you. On Monday, August 14, 2017, 9:31:38 PM GMT+1, Douglas N Greve wrote: You will need to run gtmseg --s su

Re: [Freesurfer] Mean diffusivity on cortex?

2017-08-14 Thread Douglas N Greve
You will need to run gtmseg --s subject (takes an hour or so), then add --seg gtmseg.mgz to the cmd line On 08/14/2017 04:12 PM, Shane Schofield wrote: > Hi Dr Greve, > > Are the settings correct to do partial volume correction of my MD images? > > mri_gtmpvc --i subject/dtrecon/adc.nii.gz --re

Re: [Freesurfer] Mean diffusivity on cortex?

2017-08-14 Thread Shane Schofield
Hi Dr  Greve, Are the settings correct to do partial volume correction of my MD images? mri_gtmpvc --i subject/dtrecon/adc.nii.gz --reg subject/dtrecon/register.lta --psf 0 --seg subject/mri/gtmseg.mgz --default-seg-merge --auto-mask PSF .01 --mgx 0.25 --o subject/dtrecon/adc.pvc.mgz --no-rescale

Re: [Freesurfer] Mean diffusivity on cortex?

2017-08-14 Thread Shane Schofield
Hi Dr Greve, Thank you very much! I will use the MGX CTX volume for the surface sampling.  Best Wishes,Shane. On Monday, August 14, 2017, 4:36:28 PM GMT+1, Douglas N Greve wrote: The mri_gtmpvc command will remove volume fraction effects. Look at the PETsurfer page. Run it with --psf 0 and use

Re: [Freesurfer] Mean diffusivity on cortex?

2017-08-14 Thread Douglas N Greve
The mri_gtmpvc command will remove volume fraction effects. Look at the PETsurfer page. Run it with --psf 0 and use the muller-gartner output. The output will only be valid for gray matter On 08/12/2017 10:55 AM, Bruce Fischl wrote: > Hi Shane > > we do have some tools to deal with it like > m

Re: [Freesurfer] Mean diffusivity on cortex?

2017-08-12 Thread Bruce Fischl
Hi Shane we do have some tools to deal with it like mri_compute_volume_fractions and mri_compute_volume_intensities, or maybe Doug's PET stuff. At the very least you should probably regress thickness out. cheers Bruce On Sat, 12 Aug 2017, Shane Schofield wrote: Thank you both. How can I

Re: [Freesurfer] Mean diffusivity on cortex?

2017-08-12 Thread Yendiki, Anastasia
t: Re: [Freesurfer] Mean diffusivity on cortex? Thank you both. How can I deal with partial volume in this case? Would it be possible to use the partial volume tool for PET on my MD volumes? Sorry if it is a silly idea. Best Wishes, Shane On Friday, August 11, 2017, 6:19:45 PM GMT+1, Ye

Re: [Freesurfer] Mean diffusivity on cortex?

2017-08-12 Thread Shane Schofield
Thank you both. How can I deal with partial volume in this case? Would it be possible to use the partial volume tool for PET on my MD volumes? Sorry if it is a silly idea. Best Wishes,Shane On Friday, August 11, 2017, 6:19:45 PM GMT+1, Yendiki, Anastasia wrote: Agreed, especially so with MD. K

Re: [Freesurfer] Mean diffusivity on cortex?

2017-08-11 Thread Yendiki, Anastasia
Agreed, especially so with MD. Keep in mind that you¹re upsampling MD from a lower-res (diffusion) space to a higher-res (T1) space, so it should be smooth already, relatively to measure derived from the T1. And MD varies pretty smoothly (it¹s a mean of 3 things, after all). On 8/11/17, 1:11 PM, "

Re: [Freesurfer] Mean diffusivity on cortex?

2017-08-11 Thread Bruce Fischl
Hi Shane not really - it totally depends on the size of the effect you are looking for. I would be *very* careful about partial volume effects though cheers Bruce On Fri, 11 Aug 2017, Shane Schofield wrote: Appreciate it Dr Bruce. Do you have guidelines for smoothing MD?  Dr Yendiki, I am

Re: [Freesurfer] Mean diffusivity on cortex?

2017-08-11 Thread Shane Schofield
Appreciate it Dr Bruce. Do you have guidelines for smoothing MD?  Dr Yendiki, I am trying to investigate whether cortical MD can be a marker of neurodegeneration. The idea is that during the early stages of a disease, cellular microstructure may breakdown before cortical thinning occurs. This re

Re: [Freesurfer] Mean diffusivity on cortex?

2017-08-11 Thread Bruce Fischl
Hi Shane you probably don't need cvs as it is more to extend the surface-based registration to the entire volume. Here you just need the surface-based registration I believe. Use mri_vol2surf to sample the FA onto the surface. After that it is identical to a thickness study cheers Bruce O

Re: [Freesurfer] Mean diffusivity on cortex?

2017-08-11 Thread Yendiki, Anastasia
@yahoo.com] Sent: Friday, August 11, 2017 6:42 AM To: Freesurfer support list Subject: Re: [Freesurfer] Mean diffusivity on cortex? Hi Dr Yendiki, I am studying a group of people with APOE4 and I want to see whether cortical MD increases can be detected relative to non-carriers, and if so, is

Re: [Freesurfer] Mean diffusivity on cortex?

2017-08-11 Thread Shane Schofield
Hi Dr Yendiki, I am studying a group of people with APOE4 and I want to see whether cortical MD increases can be detected relative to non-carriers, and if so, is the effect size bigger than changes in cortical thickness. On Friday, August 11, 2017, 11:19:32 AM GMT+1, Yendiki, Anastasia wrote:

Re: [Freesurfer] Mean diffusivity on cortex?

2017-08-11 Thread Yendiki, Anastasia
What effect are you trying to measure with MD on the cortex? From: Shane Schofield [shane.schofi...@yahoo.com] Sent: Friday, August 11, 2017 3:12 AM To: Freesurfer Support List; Yendiki, Anastasia Subject: Re: Mean diffusivity on cortex? Thanks Dr Yendiki. I am m

Re: [Freesurfer] Mean diffusivity on cortex?

2017-08-11 Thread Shane Schofield
Thanks Dr Yendiki.  I am more interested to compare MD in grey matter regions by putting the MD on the surface, and then do a glmfit type of comparisons. Is that OK? Would you recommend me to smooth the data after spatial normalisation? I have also used the mri_cvs_register as described on the t

Re: [Freesurfer] Mean diffusivity on cortex?

2017-08-10 Thread Yendiki, Anastasia
/AnatomicalROIV6.0 From: freesurfer-boun...@nmr.mgh.harvard.edu [freesurfer-boun...@nmr.mgh.harvard.edu] on behalf of Shane Schofield [shane.schofi...@yahoo.com] Sent: Friday, August 11, 2017 2:03 AM To: Freesurfer Support List Subject: [Freesurfer] Mean diffusivity on cortex

[Freesurfer] Mean diffusivity on cortex?

2017-08-10 Thread Shane Schofield
Hi DTI Experts, Is it sensible to do comparisons of MD on the cortex surface like a normal cortical thickness comparisons between group? If the answer is yes, are there recommended on smoothing ? DT_RECON has been completed in Freesurfer. Thank you. __

Re: [Freesurfer] Mean diffusivity (MD)

2014-07-01 Thread Alshikho, Mohamad J.
Cool ! Thanks -Original Message- From: freesurfer-boun...@nmr.mgh.harvard.edu [mailto:freesurfer-boun...@nmr.mgh.harvard.edu] On Behalf Of Douglas N Greve Sent: Tuesday, July 01, 2014 3:26 PM To: freesurfer@nmr.mgh.harvard.edu Subject: Re: [Freesurfer] Mean diffusivity (MD) The mean

Re: [Freesurfer] Mean diffusivity (MD)

2014-07-01 Thread Douglas N Greve
The mean diffusivity is the same as the apparent diffusion coef (ADC); there should be an adc volume in the output of dt_recon doug On 07/01/2014 12:38 PM, Alshikho, Mohamad J. wrote: > Thanks Doug, > Actually I want to calculate the MD just for the right and left hemispheric > white matter. >

Re: [Freesurfer] Mean diffusivity (MD)

2014-07-01 Thread Alshikho, Mohamad J.
Thanks Doug, Actually I want to calculate the MD just for the right and left hemispheric white matter. The output of dt_recon doesn't include anything about the mean diffusivity (i.e we have just the eignvals.nii ) so what is the best way to generate the MD as a nifty file? Is it by using fslspl

Re: [Freesurfer] Mean Diffusivity

2014-03-25 Thread Douglas N Greve
Sorry, I have no idea what is reasonable (I don't do a lot of DTI analysis myself). The variability in the CC is worrisome. Maybe someone else can chime in doug On 03/25/2014 06:16 AM, Rotem Saar wrote: > Hi Doug, > > Thanks for your help. > I got the attached output for the MD calculation - do

Re: [Freesurfer] Mean diffusivity

2014-02-07 Thread jwaugh
Hello all, I have run bedpostx on a series of DTI scans over ~1 year, the earlier ones in stable 5.1 and latter. I'm seeing quite a lot of variability in intensity from the earlier to later versions - re-running bedpostx in 5.3 on an older scan and comparing with 5.1 yields up to 10% variation

Re: [Freesurfer] Mean diffusivity

2014-02-06 Thread Douglas N Greve
NAME/DTI/fa-masked.mgz --sum > /usr/local/freesurfer/subjects/FOLDER-NAME/stats/all_stats_fa-masked what went wrong? You can add --seg-erode 1 to this cmd line (if you have 5.3) > > > Message: 26 > Date: Tue, 04 Feb 2014 11:10:25 -0500 > From: Douglas N Greve <mailto:

Re: [Freesurfer] Mean diffusivity

2014-02-06 Thread Rotem Saar
.mgz --sum /usr/local/freesurfer/subjects/FOLDER-NAME/stats/all_stats_fa-masked Message: 26 Date: Tue, 04 Feb 2014 11:10:25 -0500 From: Douglas N Greve Subject: Re: [Freesurfer] Mean diffusivity To: freesurfer@nmr.mgh.harvard.edu Message-ID: <52f110f1.5050...@nmr.mgh.harvard.edu> Content-Type

Re: [Freesurfer] Mean diffusivity

2014-02-04 Thread Douglas N Greve
Use mri_label2vol to transfer the wmparc.mgz into the DTI space, then use mri_segstats with --seg-erode 1 to compute summaries of the MD in each region doug On 02/03/2014 10:45 PM, Rotem Saar wrote: > Dear freesurfer experts, > > Can u please advise on how to extract the mean diffusivity value

[Freesurfer] Mean diffusivity

2014-02-03 Thread Rotem Saar
Dear freesurfer experts, Can u please advise on how to extract the mean diffusivity value for each ROI from the wmparc file ? I know how to extract the FA value, but interested in the MD value also for the same regions. Thanks Rotem Rotem Saar-Ashkenazy Department of Brain and Cognitive Science B