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My opinion (the reviewers of your manuscript may have a different one):
In general it is fine to use scans which are 10 years old. But in your case,
the problem is that all control subjects were scanned in batch 1 (date: 10y
ago/scanner 1/protocol
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Thank you. This is very helpful.
And just a follow-up question about this:
Can we use data that old? (And make a comparison to images collected this
year).
I mean is it possible to compare structural scans which were acquired such
a long time ago and
You will definitely get systematic differences between using T2 and not,
so you could have a false positive (or negative) if you are comparing
those two groups. On the other hand, you probably changed the T1
protocol a lot between now and 10 years ago, so you are likely to have
bias either
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Dear FreeSurfer Team,
We have collected T1 and T2 images in our study and running recon-all with
T2 gives us much better results (it was really good to see it).
Our aim is to compare these structural data (in Group A) to another patient
group (Group