Having just validated and started using Biocare Universal Negative Control
Serum, we were surprised when a pathologist brought back two cases in which
tumour and/or epithelium came up positive. This staining was in the same
locations as positive staining with some markers. We use Ventana
We use Biocare's Universal Negative Control Serum for our negative controls
on the Benchmark XT. I qc the IHC slides daily and don't see any staining
in the negative sections. We are a large reference lab and I see lots of
negative control slides daily.
You might have gotten a bad batch. I've