Another option:
When you fix overnight, is that with the colon opened and in fixative, or
with the tissue in cassettes in the fixative overnight? That should be fine.
Or is that placing the unfixed colon intact into the fixative overnight? If
it is this way, then the fixative has not penetrated t
Most definitely that could be the problem. A colon in the refrigerator,
although it will not be rotten, the cellular detail will be affected.
You have to coordinate with the OR for the colon to be brought to histology and
start fixing immediately, anything else will affect the quality of the
mic
