I recently had an animal from a previously undescribed mouse model die
suddenly during the weekend. Since I couldn't send it off to necropsy, I
stashed it in the refrigerator until Monday morning. According to the person
who read the histology "Post-mortem degeneration limited evaluation of most
ti
If the tissue is not fixed soon after death the microscopic morphology
will be terrible, no matter whether the animal is refrigerated or
frozen. The person suggesting refrigeration/freezing is (obviously) not
familiar with histological technique.
As someone else on the list suggested, better pla
Kirshna,
I wouldn't consider this to be a good practice. I would expect that if the
experimental study is important, thought and planning would have dictated that,
at time of necropsy, enough resources would be available to properly cover the
necropsy procedure. If an animal unexpectantly die