C4d Immunoreactivity has been used to assess transplant failure in kidneys and
hearts
Peritubular capillary deposition of C4d has been shown to be associated with
both acute humoral and vascular rejection and increased graft loss (7,8). This
was found to be independent of histological rejection
Please feel free to ask questions. I always do because I'm not in pathology
(which most people here are) but neurobiology.
Emily
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Outside of a dog, a book is man's best friend. Inside of a dog it's too dark
to read.
--Groucho Marx
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Mohamed,
Deposition of C4d is an inactive fragment of C4b (derived from complement
component C4). It provides in-situ evidence of complement activation following
alloantibody binding to graft vasculature.
As such, the development of antibodies against C4d has dramatically improved
the abil