RE: [NMusers] NONMEM codes about PK analysis from a cross-over study design

Dear Xipei I recommend you use EVID=4 at time=0 in the 2nd period on the dataset. Also you consider the relative BA(F1 parameter). ID TIME AMT DV EVID DRUG 1 0 100. 1 1 1 0.3 . 0.70 1 1 0.5 . 2 0 1 1 48

[NMusers] NONMEM codes about PK analysis from a cross-over study design

Dear NONMEM users, I have a data set from a bioavailablity study (2×2 study design). 18 people took a single dose of a marketed drug (marked as R), then after a wash-out period, took a single dose the corresponding generic drug (marked T). I want to estimate the PK parameters of T and R sep

RE: [NMusers] GPU port for NONMEM

GPU was considered in the work leading up to the upcoming parallel NONMEM.  GPU computing is intended essentially for very simple algorithms applied to a large number of very similar data sets (things like bit shifting everything left, or adding a number to every value of a matrix).  Really not we

[NMusers] GPU port for NONMEM

Hello NMUsers, Wanted to ask what has been done in terms of utilizing the bank of various GPU architecture available. Currently I have access to a few Tesla NVIDIA cards(w/ double precision math). I know PGI has worked out a solution using NVIDIA's CUDA toolkit to create a C++/Fortran complier t

Re: [NMusers] How to generate a random number with $EST

Dear nmusers, Thanks everybody. The generation of a random number from a uniform distribution finally works. Below you can see the code. You also you can see the table that NONMEM7 generated. The generated random values can be seen at the 6th column. The aim of this model is to estimate a par

RE: [NMusers] coding for sequential NM-runs

Or you could use PDx-Pop's graphical interface and it would run any runs you select either sequentially or in parallel on the number of cores you select to run on. _ From: owner-nmus...@globomaxnm.com [mailto:owner-nmus...@globomaxnm.com] On Behalf Of Xiao, Alan Sent: Tuesday, March 15,

RE: [NMusers] coding for sequential NM-runs

You could also add the full path for your input and output files for flexibility. Alan From: owner-nmus...@globomaxnm.com [mailto:owner-nmus...@globomaxnm.com] On Behalf Of Nick Holford Sent: Tuesday, March 15, 2011 6:18 AM To: NONMEM Subject: Re: [NMusers] coding for sequential NM-runs Ma

Re: [NMusers] coding for sequential NM-runs

Markus Hope that this answers your question : Write a code like this (use of nmgo Wings command here) call nmgo d4d call nmgo d4d2 call nmgo dat4c call nmgo dat4d or with nmfe6 or 7 call nmfe d4d call nmfe d4d2 call nmfe dat4c call nmfe dat4d The d***are control streams Then save it in in a

Re: [NMusers] coding for sequential NM-runs

Markus, I don't know if this is what you need, but I was using this code (below) in a batch (.bat) file to run a model, then update the initial estimates, and then run the resulting model. This uses the Perl Speaks NONMEM scripts "execute" and "update_inits", but I guess you can modify the indi

Re: [NMusers] coding for sequential NM-runs

Markus, Create a file called myruns.bat in a text editor Insert lines like this in file: call nmfe7 run1.ctl run1.lst call nmfe7 run2.ctl run2.lst Save the file myrun.bat (be sure it is not saved with a .txt extension!) in the same directory as the NM-TRAN control streams run1.ctl, run1.ctl

[NMusers] coding for sequential NM-runs

dear community, I wonder if someone can provide me a coding for starting (automatically) sequential NM7-runs from MS-DOS? thank you in advance and kind regards Markus -- Markus Joerger MD PhD Department of Medical Oncology Cantonal Hospital Rorschacherstr. 95 9007 St. Gallen Switzerland markus