Re: [NMusers] Growth Curve Modelling

2011-02-23 Thread Nick Holford
Nyasha, Thanks for your further explanation of what you want to do. You can easily adapt the NM-TRAN code for the model for WT based on PMA in order to compare your PMA-SEX-WT data you have with the model predictions. I looked at the 3 papers you mention below -- Beath describes a model for

Re: [NMusers] Growth Curve Modelling

2011-02-23 Thread nyashadzaishe mafirakureva
Hi Nick and Joe, Thank you very much for your responses. Well, I must say I'm a real beginner in modelling and this is my first attempt at growth curve modelling. I was of the idea that growth curves have been developed and in use for quite sometime and hence it would be possible to find a functio

Re: [NMusers] Growth Curve Modelling

2011-02-17 Thread Nick Holford
Hi, Thank you Joe for noticing the recent publication of a quantitative model relating age and sex to weight across the human life span (Sumpter & Holford 2011). The WHO growth charts are just that -- charts i.e. a picture with some lines on it. The model that Anita and I have proposed is qu

RE: [NMusers] Growth Curve Modelling

2011-02-17 Thread Standing Joseph (GREAT ORMOND STREET HOSPITAL FOR CHILDREN NHS TRUST)
Nyashadzaishe, UK and I believe WHO growth charts are derived using LMS method which you can do in R - look for papers by TJ Cole. I also suspect you might get a response from a certain NHG Holford telling you to look at his NONMEM method: Paediatr Anaesth. 2011 Mar;21(3):309-15 - I have only s