Our critical value triggering a phone call to the RN or MD is 4. This level was 
used as it drives a critical decision to initiate EGDT. As an emergency 
physician, this upper level is acceptable for me since the nature of my 
practice necessitates me to have reviewed all the labs in the few hours I 
provide care (I'll be aware of all lactate levels nearly real-time and can take 
appropriate action). For a patient on the inpatient floor, however, the 
attending physician may not know of results for 12-24 hours if not notified. 
Without knowledge of the result, the opportunity to re-evaluate the plan and 
potentially change the level of aggressiveness might be lost. If the physicians 
in your hospital generally agree a lactate level >2.2 would generally prompt a 
different approach at that point, then it seems prudent to set your critical 
value there. Maybe they will suggest 2.5 or 3. The goal around picking a 
critical value, therefore, are more about prompting an action - more aggressive 
fluid administration, potentially a transition to a level of care allowing 
closer monitoring, prompt to order a follow up lactate to follow its trend, 
etc. Here are two studies showing the how increasing lactate is independently 
associated with mortality - perhaps they will help provide some "scientific" 
support to your policy making. 

Annals EM 2005; 46(3)
Shapiro, Annals of EM 45 (5), 2005

Since the studies both show increased mortality even with lactates in the 2's, 
it seems reasonable to, at least, be considered "important" information; and 
sharing it with the physician will likely drive an action(s) to prevent 
worsening of condition - or getting to a lactate of 4!. 

Jeff Vespa, MD
Medical Director, Quality and Patient Safety
North Memorial HealthCare & Level I Trauma Center
Robbinsdale, MN 



>>> "Coon, Joshua" 05/03/12 10:20 AM >>>

Can anyone help me during my sepsis collaborative this year we are looking to 
implement Lactic acid as one of the values if critical it is reported. Has 
anyone established a critical result for lactic acid. We have in our policy 
that the values greater than 2.2 are high. No critical has been established. 
And does anyone have literature on this topic? Thanks .

"Always the Best"
Joshua
Joshua Coon RN CEN
Emergency Department Administrative Charge Nurse
Florida Hospital Waterman
(352) 253-3264
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