Hello group,

I have a question on the CMS bundle and the revised SCCM guidelines concerning 
volume resuscitation and application of vasopressors.   The 3 hours bundle 
states fluid 30ml/kg for hypotension or lactate >4.  The 6 hour bundle states 
to apply vasopressors for hypotension that does not respond to initial fluid 
resuscitation.   Is the recommendation to add vasopressor after 30ml/kg or can 
the provider give more fluid and then within the 3-6 hour window then apply 
vasopressors for sustained hypotension?  There is discussion among our team 
referring to the ARISE trial and that the variable of  vasopressor therapy did 
not change outcomes.  Any insight on the perspective of others is appreciated.  
Jeanie Bollinger


Jeanie Bollinger MSN,RN,ACCNS-AG, CCRN
Sepsis Clinical Nurse Specialist
Nursing Department of Excellence
Mission Health
Asheville, NC

Phone: 828-213-7171
Beeper: 828-207-2363



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