Hi, all-

Based on traditional definition for severe sepsis, is it appropriate to use an 
increased need in O2 as an indicator of sepsis associated organ dysfunction 
when the source of infection is in the lungs, ie PNA? Clearly if the lungs have 
infection oxygenation needs likely will increase, yet this isn't necessarily 
related to a hypo-perfused state.

We have many patients coming in with  bacterial PNA or COVID PNA and they are 
placed on supplemental O2, 2+ SIRS present, lactate<2, normotensive, no other 
signs of end-organ dysfunction. Do we use need for supplemental O2 as organ 
dysfunction? I would say NO.

Historically in my sepsis work we only used this criteria if  remote from the 
site of infection. I am looking for validation of this and have a hard time 
finding literature to support.

I would appreciate your thoughts.
Thanks!

Jessica Harkey, MSN, RN, ACCNS-AG
Manager, Sepsis Quality
Quality, Safety and Risk
2500 Grant Road, Mountain View, CA 94040
650-988-7968 Office
661-330-2396 Cell
[email protected]<mailto:[email protected]>
elcaminohealth.org<www.elcaminohospital.org>
[cid:[email protected]]
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