I guess my reaction is typically me.
Does it really matter if the effectiveness is broadly
excepted?
Silver kill bacteria. Case Closed.
Molecular? Isn't everything? It isn't magnetic. That
changes everything.
i guess I feel no evangelistic tendency towards the
usage of anything unless it is threatened by a law
that changes access and usage rights.
I'd like to see as much research as possible. I am not
threatened by spin. Everything goes into the
information pot.
=z=
--- Pat <pattycake29...@yahoo.com> wrote:
> The link you sent said not found. This is what I
> found at Sloan-Kettering
>
> ( http://www.mskcc.org/mskcc/html/69189.cfm ) ,
> not exactly what I wanted to hear.
>
>
> Pat
>
> Common Name
> Silver Proteins, Colloidal Silver Proteins,
> Colloidal Silver Water
> top
> ________________________________
>
> Clinical Summary
> Colloidal
> silver consists of silver particles suspended in a
> liquid. It is often
> produced by home-made generators. The use of silver
> medicinals to treat
> disorders such as epilepsy, gonorrhea, and colds was
> not uncommon until
> the mid-20th century. However, silver was replaced
> by safer therapies
> in the recent decades. While silver compounds are
> still used in
> external preparations as antiseptics, there has been
> a growing interest
> in using the collodial form of silver orally as an
> alternative
> medicine. Although no human clinical data support
> the use of oral
> colloidal silver, it is being promoted as a cure for
> AIDS, cancer, and
> diabetes. Silver is not an essential mineral and
> does not serve any
> physiological function in the body. It actually
> denatures proteins by
> binding to their reactive groups. It can inactivate
> some enzymes by
> forming hemisilver sulfides with sulfhydryl groups
> of the enzymes (1).
> Silver when taken orally can interact with and
> reduce the effectiveness
> of tetracycline, quinolone, and penicillamine. Long
> term use can cause
> silver deposition in the skin and mucous membranes
> leading to an
> irreversible condition called argyria, characterized
> by bluish-gray to
> gray-black pigmentation (2) (3). Other adverse
> effects include seizures (6) and kidney damage.
> Pregnant women should not consume colloidal silver
> as it can cause developmental abnormalities in the
> fetus (1).
> top
> ________________________________
>
> Purported uses
> * AIDS
> * Cancer treatment
> * Diabetes
> * Immunostimulation
> * Infections
> top
> ________________________________
>
> Constituents
> * Silver particles suspended in liquid.
> top
> ________________________________
>
> Mechanism of Action
> Silver
> is unstable in suspension form and can bind to
> proteins. Silver
> compounds form hemisilver sulfides with sulfhydryl
> groups that leads to
> inactivation of enzymes. Silver also has the ability
> to bind amino,
> carboxyl, phosphate and imidazole groups (1).
> Studies have shown that silver accumulates in rat
> liver and binds with
> various tissues and basal membranes. It also affects
> the activities of
> lactate dehydrogenase and glutathione peroxidase and
> the peroxidation
> of membrane lipids (4).
> top
> ________________________________
>
> Pharmacokinetics
> Approximately
> 10% of silver salts may be absorbed following
> ingestion, with increased
> absorption from ruptured mucus membranes and skin
> wounds. The half-life
> varies from several days to months but silver
> deposited in the skin has
> a much longer half-life. It is excreted into the
> bile and eliminated in
> the feces (1).
> top
> ________________________________
>
> Warnings
> The
> Food and Drug Administration (FDA) declared that all
> over-the-counter
> drugs containing colloidal silver are not recognized
> as safe and
> effective and are misbranded (7).
> The FDA has also recently issued letters to website
> operators of
> colloidal silver warning them that it is illegal to
> promote such
> products online (8).
> top
> ________________________________
>
> Contraindications
> Pregnant women should not use colloidal silver as it
> can cause developmental abnormalities in the fetus
> (1).
> top
> ________________________________
>
> Adverse Reactions
> Reported (Oral): Accumulation
> of silver in the body causes argyria, a bluish-gray
> discoloration of
> the skin, which is untreatable. Other effects
> include seizures and
> kidney damage.
> Reported (Topical): Topical use of silver nitrate
> for burns may cause methemoglobinemia.
> Exposure to high concentrations of silver, such as
> in an industrial setting, leads to systemic toxicity
> (1) (5).
> top
> ________________________________
>
> Herb-Drug Interactions
> * Antibiotics: Colloidal silver can reduce the
> bioavailability of antibiotics such as tetracycline
> and quinolone.
> * Penicillamine: Colloidal silver can reduce the
> effectiveness of drugs such as penicillamine by
> binding to the drug.
> top
> ________________________________
>
> Literature Summary and Critique
> No
> human studies have been conducted to test the
> medicinal effects of
> colloidal silver. There are a few case reports on
> its toxicity.
>
> McKenna JK, et al Argyria associated with colloidal
> silver supplementation. Int J Dermatol 2003;
> 42(7):549.
> A
> 65-year old male developed skin discoloration but
> had no other
> symptoms. He had consumed colloidal silver
> supplements for two years
> for treatment of diabetes. The discoloration was
> limited to fingernails
> but could not be treated by depigmenting creams or
> chelation. The
> patient was advised to use sunscreens to prevent
> further pigmentary
> changes.
>
> Gulbranson SH, Hud JA, Hansen RC. Argyria following
> the use of dietary supplements containing colloidal
> silver protein. Cutis 2000; 66(5):373-374.
> A
> 56-year old man developed bluish discoloration of
> fingernails (argyria)
> following consumption of colloidal silver for cold
> and allergy for 3
> years. There was no improvement in the appearance of
> fingernails 3
> months after the patient stopped consuming colloidal
> silver. He was
> advised to avoid sun exposure to prevent further
> discoloration.
>
> Mirsattari SM, et al. Myoclonic status epilepticus
> following repeated oral ingestion of colloidal
> silver. Neurology 2004;62:1408-10.
> A
> 71-year old man developed myoclonic status
> epilepticus and coma
> following daily ingestion of one ounce of colloidal
> silver and various
> herbal remedies for stage B adenocarcinoma of the
> prostate for a period
>
=== message truncated ===
=z=
The novelist, journalist and psychologist
Michael Zangari
http://zangarijournalism.com
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