Hi Roger,

On Mon, 20 Nov 2000 15:47:24 EST, rogalt...@aol.com wrote:

>In a message dated 11/20/00 3:39:22 PM EST, dtmil...@midiowa.net writes:
>
><< From the report: 
> "Investigators have hypothesized that this toxicity is related to a
> silver-induced selenium deficiency that inhibits the synthesis of the
> seleno-enzyme glutathione peroxidase.  In animals supplemented with
> selenium and/or vitamin E, exposures of silver as high as 140
> mg/kg/day (100 mg Ag/L drinking water) were well-tolerated (Bunyan et
> al., 1968). "
> 
> Now we know where the glutathione peroxidase comment came from (the
> MD's rant).  
> 
> -- Dean -- from (almost) Duh Moyn  (CDP, KB0ZDF) >>
>
>Dean: Well, then you'll have to explain what they're saying here. First, they 
>say that a certain kind of toxicity is caused by low selenium levels induced 
>by the presence of silver (how much?). Then they say that (what appears to be 
>a huge intake of) silver can be well tolerated. Translation please. Roger

I should have explained why I posted this quote.  :)

The MD in a message last week stated that CS can produce glutathione
peroxidase deficiency, and I went looking for the source for that
comment.  I didn't find it (so I didn't post any message about it).

However, this EPA report seems to provide the source.  But the MD got
it wrong, as I had suspected.

The deficiency occurs only when there is also a deficiency in both
selenium and vitamin E.  So ... it's a vitamin/mineral deficiency that
produces the problem, not CS.

-- Dean -- from (almost) Duh Moyn  (CDP, KB0ZDF)


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