Subject: Silverlon Date: Sat, 25 Aug 2001 09:32:22 -0400 From: Bart Flick <[email protected]> Organization: argentum To:*Silver-List* <[email protected]> CC: Tom Miller <[email protected]>, SILVER <[email protected]> A.B.Flick MD writes: My partner and CEO of Argentum Medical, Mr. Gregg Silver, asked that I comment on recent E-mails. With respect to Mr Andersons comments 24 August 2001: 1. The antimicrobial activityof silver rests upon the interaction of silver with the bacteria's cellular membrane. This interaction can occur through the presence of a silver ion in solution or the release of
silver in an ionic moiety directly from the surface of metalic silver when a bacterial cell membrane comes in direct contact with the metalic surface. With respect to Silverlon the antimicrobial activity is a result of free silver ions (released through a silver oixide intermediate) in solution interacting with the bacterial cell membrane or direct contact of the bacterial cell membrane on the metalic surface. The metalic surface area of Silverlon is at least 1000 fold greater that the geometric surface area of the fabric due to the uniform circumferential plating of metalic silver to the polymer substrate and the molecular terrain (shown on tunneling electron microscope). As with the reference to water filtratio, the name of the game in antimicrobial activity is surface area. 2. Driving silver ions via an electrical gradient increases the ionic silver release between 4 to 8 fold as well as the depth of penetration of silver ions into the surrrounding tissue. Bimetalic applications is directly dependent upon the surface area of the bimetalic junctions with metals more noble that silver (i.e. gold platinum etc) but not less noble (i.e. copper) 3. The patents will give one only a brief overview. 4. Silver ions in the proper concentration cause fibroblasts to alter their normal cellular morphology. To say that silver ions create stem cels is unfounded from my reading of the literature and my work over the past 25 years. With respect to Marshall's comments 24 August 2001: 1. The finger tip amputation case was my patient. The tip was amputated through the lower third of the nailbed with the nail matrix intact. 2. With respect to amputated finder tips in children, please refer to the Illingsworth paper in the early 1970's. The key to understanding this case rests with understanding the basic mechanisms of mainatining a "blastema". From my experience three key elements are essential: (1) proper moisture levels, (2) proper conductivity and (3) proper control of wound bioburden. With respect to Solar's comments 24 August 2001: 1. Agree that all silver containing products are NOT equal. 2. With reference to Dr. Becker statements, I do not feel that the comments as quoted are not completely correct. While a medical student in the 1970's, I had the opportunity to work in Dr. Becker's lab. I have the greatest respect for his creativity and intelligence. But I stand behind my comments referenced above. With kind regards, Bart Flick M.D. -- The silver-list is a moderated forum for discussion of colloidal silver. To join or quit silver-list or silver-digest send an e-mail message to: [email protected] -or- [email protected] with the word subscribe or unsubscribe in the SUBJECT line. To post, address your message to: [email protected] Silver-list archive: http://escribe.com/health/thesilverlist/index.html List maintainer: Mike Devour <[email protected]>
