John
I hope your into reading semi technical stuff.
VANADIUM
Rough file:
"When Dr. John McNeill, dean of pharmaceutical sciences at UBC, and his
colleagues Clayton Heilinger and Arun Tahiliani were testing vanadium - a
common trace element found in seaweed - on diabetes induced female rats to
see if it would prevent the development of cardiac problems, they made a
startling discovery. Vanadium not only improved the rats' cardiovascular
performance, it also regulated the levels of glucose in their blood and
prevented the formation of cataracts. In fact, the rats that were fed
vanadium in their drinking water appeared normal in all respects. ... Adds
McNeill: 'The fact that vanadium appears to fix the whole system is a very
nice discovery. It was not something we originally intended to look for.'
On average, an adult consumes one to four milligrams of vanadium every day
from such foods as meat, milk, vegetables and bread: fish and marine plants
are particularly good sources. The biological importance of vanadium,
however, is largely unknown. A natural part of the regulatory system, it is
believed to prevent cholesterol formation both in blood vessels and in the
central nervous system. ... However, says McNeill, 'we never thought
vanadium would do it [mimic insulin] so well. From everything we looked at,
the rats were completely normal."
A two-factor, two-by-three factorially arranged experiment was performed to
ascertain whether iodine affects the response of rats to vanadium
deprivation. Male weanling Wistar-Kyoto rats were fed a 16% casein 68%
acid-washed ground corn diet for 8 weeks. The variables were supplemental
vanadium at 0 or 1 microgram/g and supplemental iodine at 0, 0.33 or 25
micrograms/g. Vanadium deprivation increased thyroid weight and thyroid
weight/body weight ratio and decreased the concentration of vanadium in
liver. Vanadium and iodine interacted such that, as dietary iodine was
increased, plasma glucose increased in the vanadium-deficient rats but
decreased in the vanadium-supplemented rats. Also, as dietary iodine was
increased, thyroid peroxidase activity decreased; the decrease was more
marked in the vanadium-supplemented than the vanadium-deprived rats. The
findings suggest that vanadium may have a physiological role affecting
iodine metabolism and thyroid function.vanadium and iodine interaction
effects on thyroid.doc
The following study shows that vanadium supplementation can increase bone
mineral levels and that there is an interaction between vanadium and
vitamin C in cholesterol metabolism.
Magnes Trace Elem 1991-92;10(5-6):327-38
Vanadium and ascorbate effects on 3-hydroxy-3-methylglutaryl coenzyme A
reductase, cholesterol and tissue minerals in guinea pigs fed low-chromium
diets.
Seaborn CD, Mitchell ED, Stoecker BJ
Department of Nutritional Sciences, Oklahoma State University, Stillwater.
Vanadium has been reported to affect numerous physiological processes;
however, a demonstration that vanadium deficiency consistently impairs
biological function is lacking. The purpose of this study was to determine
if the activity of hepatic 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA)
reductase, the rate-limiting enzyme in cholesterol synthesis, is affected
by dietary supplementation of vanadate and/or chronic ascorbic acid
deficiency. To determine if vanadium and/or ascorbic acid affected mineral
metabolism, tissue minerals also were analyzed. Weanling male guinea pigs
were assigned randomly to groups of 10 in a 2 x 2 factorial design. The
dietary variables were ascorbate, 0.5 or 10 mg/day, and vanadium < 0.01
microgram or 0.5 microgram/g diet as NH4VO3 in a low Cr diet containing <
0.07 microgram Cr/g diet. After 21 weeks on this diet, guinea pigs
receiving more ascorbate had lower liver weight/body weight ratios and
increased bone copper. Testes weight/body weight ratios, hepatic glycogen
and bone copper decreased while hepatic lipids, fecal bile acids, plasma
cortisol and bone calcium and magnesium were increased by vanadium
supplementation. An interaction between vanadium and ascorbate affected
cholesterol excretion in feces, hepatic iron, plasma cholesterol
concentration and the activity of HMG CoA reductase. This study provides
evidence of increased bone mineral concentrations with vanadium
supplementation and of an interaction between vanadium and ascorbate which
affected cholesterol metabolism.
Regards
Graham
At 02:36 PM 4/25/03 -0500, you wrote:
Catherine,
Thank you for the URL. I looked and read the whole item and still would be
reluctant to use the Vanadium to control my blood sugar level. It's just to
dangerous. (as documented by these items) I am a regular user of CS and
would be happy to expound on my personal experiences with it. But, I need
more certification that Vanadium would be safe to use.
I hope you do well with your Sars work. Be careful and stay healthy.
John.
----- Original Message -----
From: "C Creel" <ccr...@adelphia.net>
To: <silver-list@eskimo.com>
Sent: Friday, April 25, 2003 8:39 AM
Subject: Re: CS>Re:CS and Diabetes
> Dear John,
>
>
> I think this is a well-balanced presentation on Vanadium.
>
> http://www.diabetesnet.com/vanad.php
>
> Regards,
> Catherine
>
>
>
>
>
>
>
>
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