Dear Garnet,

Thank you very much for the warning. I had
reached about the same conclusion, but for
entirely different reasons. The boiling point of
DMSO is far above the boiling point of H2O. So
common distillation apparatus would be misused
if they were used to purify DMSO. It could be
quite hazardous, aside from the toxicity you
point out. Phase transitions have a purifying effect,
so why not use the freeze-thaw transition instead of
the boil-condense transition? IMHO, trying to
distill DMSO offers no advantages and perhaps plenty 
of drawbacks.

Thanks again for your input.

Best regards,

Matthew
----- Original Message ----- 
From: "Garnet" <garnetri...@earthlink.net>
To: "Matthew McCann" <mmcc...@franciscan.edu>
Sent: Sunday, October 17, 2004 12:37 PM
Subject: Re: CS>Refining DMSO


> Just wanted to mention that inhaling DMSO vapors, that is boiling it and
> inhaling the "steam" is toxic. It has a very high boiling point, over
> 350*. This is the one way it can be dangerous to humans.
> 
> It is however safe to nebulize it since that is not DMSO vapor but DMSO
> liquid in very small droplets.
> 
> Garnet
> 
> On Sat, 2004-10-16 at 19:37, Matthew McCann wrote:
> > Subject: Refining DMSO
> > 
> > http://www.designscientific.com/applications.htm
> > http://www.designscientific.com/zonetheory.htm
> >  
> > These websites refer to zonal melting as a physical method
> > of ultra-purifying organic compounds. E.F.G Herrington's
> > text Zonal Melting Of Organic Chemicals (John Wiley,
> > 1963) describes  many organic compounds that have
> > been successfully purified that are less convenient
> > than DMSO regarding volatility, freezing temperature,
> > toxicity, handling, availability, etc.
> >  
> > It might be possible to make DMSO zonal
> > refing apparatus from a
> >  bulkheaded angel-food cake mold on a veeerry slow
> > turntable spot-heated by an incandescent lamp.
> >  
> > Matthew
> 


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