I too have been experimenting with "cansema" and its effects on skin  
cancers.  I had over the
months developed an island of raised skin covering the front 1/3 of  my nose 
which in places
had turned purple, and in one place flaked and left raw.  I  applied the 
"new" cansema salve to
the affected area a week ago Tues, and am now in my 10th day.   After about 
6-7days my
nose was quite sore and had grown about 1/16-1/8 of eschar before it  started 
a gradual slof-
fing.  The sloffing has stopped now and the majority of eschar  is gone, but 
my nose is somewhat pitted in places, like having been in a  car accident or 
fight.  I received many com-
ments at work during this process as you might imagine(I didn't have  my nose 
covered the
total time). Some of the pits(gouges) seem about 1/8" deep and  started to 
ooze, so I cleaned
with h2o2 and applied Neosporin to stop infection and help heal. As  of now 
my nose looks and feels like cardboard, but I feel time will  heal.  Pete