Hi,
I understand the 'property' of Manuka honey that fights bacteria, is
hydrogen peroxide.  I'd be glad to hear if this not correct.

Jean

They seem to be saying all honeys produce Hydrogen peroxide, and that Manuka 
honey has some extra qualities also exhibited by some other honeys.

Some quotes:
The potency of honey's healing properties depends on the type of flowers 
from which the bees gather their nectar. Honey from New Zealand's native 
Manuka tree, which the indigenous Maori people used as a medicinal plant is 
receiving worldwide attention for wound treatment. Manuka honey contains a 
special, non peroxide antibacterial component not found in other honey, 
trademarked as Unique Manuka Factor (UMF), which is the standard description 
of its anti-bacterial activity.

To determine UMF strength, honey is exposed to cultured bacteria. The amount 
of honey needed to stop bacterial growth is measured and compared to the 
bacteria retarding effect of a phenol and water solution. The amount of 
phenols in this comparison water determines the UMF of the honey being 
tested. Ordinary Manuka has a UMF of approximately 4-5. UMF 10+ is honey 
whose antibacterial action is equivalent to at least a 10% phenol solution. 
Its antibacterial activity is over double the strength of standard 
antiseptic (4% carbolic acid). UMF 18+ has the strongest antibacterial 
activity yet is still safe to consume.

The advantage of the UMF is that it does not need to be diluted to be 
effective unlike honey's hydrogen peroxide producing enzyme. Since the UMF 
Is not broken down by body tissue enzymes, like the hydrogen peroxide 
producing enzyme, manuka provides stronger antibacterial action on a wound 
than other honey. The UMF penetrates skin tissues easily, reaching deep 
seated bacterial infections which the hydrogen peroxide fails to do. The 
higher the antibacterial potency of the honey, as denoted by its UMF rating, 
the deeper the antibacterial activity will reach to clear infection.

Applied topically, Manuka honey effectiveness has been shown in management 
of varicose ulcers, minor burns, cuts and wounds, overcoming the seven most 
common germs associated with wounds. It provides a moist, sterile 
environment for skin regeneration and contains antioxidant activity which 
decreases amounts of destructive free radicals and prevents fibrotic 
scarring. The anti-inflammatory agents it contains reduce swelling and 
contribute to pain relief. It increases blood circulation to the area and 
its osmotic effect draws exudate from the wound. Manuka honey also provides 
nutrients and oxygen, stimulating tissue regrowth. Its debriding action 
allows easy detachment of dead tissue and reduces wound odour by preventing 
ammonia production. By creating a barrier between the wound and dressing, it 
makes dressing removal easier, preventing damage to regenerating tissue. 
Unlike pharmaceutical antibacterial agents, Manuka honey does not damage 
emerging healthy skin. It is filtered to remove fine organic substances that 
may cause allergic reactions in the wound. 
http://www.littletree.com.au/manuka.htm



Active manuka honey contains an additional component found only in honey 
produced from Leptospermum plants: unique manuka factor (UMF).  Honey with 
UMF is more effective than that with hydrogen peroxide against some types of 
bacteria. Medical professionals in New Zealand use active mauka honey with a 
rating of 10 UMF or higher.   Chemical Composition  More than 180 compounds 
have been identified in propolis, and many are biologically active. 
Flavonoids are abundant, including apigenin, galangin, kaempferol, luteolin, 
pinocembrin, pinostrobin and quercitin. 
http://www.lifetimehealth.com/en/page.asp?E_Page=209561&product=225400





When most honeys are diluted they release hydrogen peroxide (the same 
chemical that is in household bleach) which kills bugs. Manuka honey has a 
different action. It produces some natural chemicals that kill bacteria. 
http://www.burkesbackyard.com.au/2000/archives/2000?p=1725



Much research effort has centred on establishing the properties of honey to 
which its antibacterial activity may be attributed. Such factors as 
osmolarity, acidity, hydrogen peroxide content and chemical components of 
honey have all been considered to contribute to the inhibition of bacterial 
growth. Honey is a highly saturated sugar solution which could suggest that 
this characteristic of honey would convey an antimicrobial effect. The high 
concentration of sugars leaves very little available water for the growth of 
microorganisms. However, the osmolarity of honey does not appear to be a 
major factor. The acidity of honey has also been suggested to explain the 
antibacterial activity of honey. Honey contains many organic acids, 
predominantly gluconic acid produced from glucose by glucose oxidase, and is 
characteristically acidic with pH 3.2 to 4.5. Although such an acidity level 
would be inhibitory to the growth of most bacterial species, there appears 
to be no correlation between antibacterial activity and the acidity of the 
honey. There is much evidence to suggest that the antibacterial activity of 
honey is due to more than the sugars present therein. Two major sources have 
been shown to be responsible for the anti-microbial activity - hydrogen 
peroxide (from the bee) and uncharacterised chemical substances (from the 
floral source). Hydrogen peroxide is known to have antimicrobial properties 
and can be removed efficiently by the addition of catalase to the honey 
prior to testing for antibacterial activity.

This project has investigated the correlation between antimicrobial activity 
and the non-peroxide activity of particular Leptospermum-derived honeys. 
Initial investigations tested the efficacy of these honeys against one 
particular bacteria (Staphylococcus aureus), while later studies assessed 
the effect of this honey on a range of food pathogens, animal pathogens 
(e.g. in mastitis) and human pathogens (e.g. golden Staph). Using honeys 
sourced from around Australia and screened against several reference 
microorganisms, the anti-microbial potency of one particular Australian 
honey (from Leptospermum polygalifolium) was shown to be comparable to NZ 
Manuka honey (from L.scoparium). The results of this screening of active 
honeys against pathogenic bacteria has supported the registration of honey 
by Capilano Honey Limited as a "Drug" with the Therapeutic Good 
Administration based on its antimicrobial activity.

This project was undertaken to add value to the existing honey resource by 
developing products with therapeutic benefit (i.e. for the treatment and 
management of moist wounds such as leg ulcers).

Specific geographic region(s) in Australia which produce "active" honey have 
been identified, the potency of the Leptospermum-derived honeys against a 
range of bacteria has been defined, the particular chemical characteristics 
of these honeys have been examined, and the honey has been registered as a 
"Drug" with the Therapeutic Good Administration. Work is continuing to 
better define the specific agents responsible for the antimicrobial activity 
(which have been elusive to date) and to evaluate the opportunity for 
therapeutic benefit from honey beyond its antimicrobial activity (i.e. its 
direct wound healing benefit). 
http://www.rirdc.gov.au/reports/HBE/05-159sum.html



In contrast to TTO, honey has a much longer recorded history of medicinal 
use. Scattered reports in the medical literature describe the antibacterial 
properties of honey and honey products, and their potential as antimicrobial 
agents, particularly in wound care.20 More recently, in vitro antibacterial 
activity has been described and a wide range of organisms is inhibited by 
honey including E. coli, Proteus mirabilis, Ps. aeruginosa, Enterococcus 
faecalis21 and Helicobacter pylori.22 The activity of honey has been 
attributed to the high osmolarity, the low pH and the presence of hydrogen 
peroxide. However, these factors alone or in combination do not account for 
all of the antibacterial activity and the identity of the main antimicrobial 
component of some honeys and its mechanism of action remains unclear. 
http://www.health.gov.au/internet/wcms/Publishing.nsf/Content//cda-pubs-cdi-2003-cdi27suppl-htm-cdi27supab.htm



 Research at Waikato University, in Hamilton New Zealand by Dr Peter Molan 
and others has shown that whilst all honey has healing properties, a special 
form derived from the New Zealand Manuka bush, (Leptpospermum scoparium) 
contains special ingredients not present in honeys derived from other floral 
sources. This has led to the use of the mark UMF® (Unique Manuka Factor) on 
some specially tested Manuka honeys indicating they contain these compounds. 
While all honeys contain the hydrogen peroxide that gives them a mild 
antibacterial action, UMF® honeys have much higher antibacterial effects not 
related to hydrogen peroxide, but due to the Unique Manuka Factor. 
http://www.thexton.com.au/product/Manuka__Honey__UMF__5%2B__500g





I don't know how the New Zealanders pronounce Manuka.

There is a suburb in Canberra, ACT, called Manuka.  I called it Manooka, of 
course.  I had no idea where people lived if they said they lived in 
Marnaka, until I found out that's how they were pronouncing Manuka.    (Kind 
of "Maah - nuh - kuh).



Rowena


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