It can be done through AppleScript, however. The following sets each page's 
bounds to the content bounds on three sides, also subtracting off the built-in 
10-pixel boundary normally used by Auto Crop, then adding back in on the 
appropriate side a gutter (which when viewed in Facing Pages) of total size 
gutterSize (up to the original bounds of the page - it can't add in a gutter 
that doesn't exist in the underlying PDF). 

set gutterSize to 50
tell application "Skim"
        tell document 1
                set thePages to pages
                set isOdd to true
                repeat with thePage in thePages
                        set theContentBounds to (content bounds of thePage) -- 
L T R B
                        set item 2 of theContentBounds to (item 2 of 
theContentBounds) - 10
                        set item 4 of theContentBounds to (item 4 of 
theContentBounds) + 10
                        if isOdd is true then
                                set item 1 of theContentBounds to (item 1 of 
theContentBounds) + 10
                                set item 3 of theContentBounds to (item 3 of 
theContentBounds) - 10 + (gutterSize / 2)
                                set isOdd to false
                        else
                                set item 3 of theContentBounds to (item 3 of 
theContentBounds) - 10
                                set item 1 of theContentBounds to (item 1 of 
theContentBounds) + 10 - (gutterSize / 2)
                                set isOdd to true
                        end if
                        set bounds of thePage to theContentBounds
                end repeat
        end tell
end tell


On 2010-03-05, at 2:13 PM, Christiaan Hofman wrote:

> 
> On Mar 5, 2010, at 21:00, Sophie wrote:
> 
>> I often crop my PDFs in Skim to eliminate white-space and get more  
>> readable font size on screen, reading 2 pages side-by-side. It works  
>> great. One small side effect, though, reduces the readability: when  
>> the white space is removed, the text column for left and right pages  
>> come very close together, as the gutter separating the two pages  
>> remains the same.
>> 
>> So the 2 text columns become crunched together in the middle, while  
>> there is a lot of empty space to left + right of the screen.
>> 
>> Any way the gutter size could be made tweak-able e.g. via a  
>> preference, or intelligently enlarge itself?
>> 
>> Thanks!
> 
> No, that's not possible. 
> 
> Christiaan
> 
> 
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