Thanks for the quick reply guys! Changing the min amino acids worked
perfectly

On Jan 6, 7:14 pm, Ulrich auf dem Keller <[email protected]>
wrote:
> change -l flag in xinteract from -l7 to -l1
>
> p0.05 -l7 -x20 -O
>
> p0.05 -l1 -x20 -O
>
> can be done in Petunia by setting minimum number of amino acids from  
> default 7 to 1
>
> Ulrich
>
> On Jan 6, 2009, at 2:39 AM, dre wrote:
>
>
>
> > Hi everyone,
> > I have been trying all morning to get the proteomic pipeline to work
> > for me, but it keeps giving me the same error msgs. First I tried
> > using Mascot's export option to directly save the database search
> > results as a pepXML file so that I could start directly at step 5 of
> > the TPP and proceed with the peptide and protein prophet analysis, but
> > this produced an error. Then I tried to start at the beginning of the
> > pipeline and everything worked perfectly until the peptide prophet
> > step. When I add my 6 pepXML files to the step 5 and run peptide
> > prophet without any additional settings, I get the same error as
> > before, which goes as follows:
>
> > ----------------------------------------------------------------------------------------------------------------------------------------------------------------
>
> > run_in c:/Inetpub/wwwroot/ISB/data; xinteract  -Ninteract.pep.xml -
> > p0.05 -l7 -x20 -O c:/Inetpub/wwwroot/ISB/data/QMIX1_01.pep.xml c:/
> > Inetpub/wwwroot/ISB/data/QMIX2_01.pep.xml c:/Inetpub/wwwroot/ISB/data/
> > QMIX3_01.pep.xml c:/Inetpub/wwwroot/ISB/data/QMIX4_01.pep.xml c:/
> > Inetpub/wwwroot/ISB/data/QMIX5_01.pep.xml c:/Inetpub/wwwroot/ISB/data/
> > QMIX6_01.pep.xml
>
> > xinteract (TPP v4.1 JETSTREAM rev 1, Build 200811121809 (MinGW))
>
> > running: "C:/Inetpub/tpp-bin/InteractParser "interact.pep.xml" "c:/
> > Inetpub/wwwroot/ISB/data/QMIX1_01.pep.xml" "c:/Inetpub/wwwroot/ISB/
> > data/QMIX2_01.pep.xml" "c:/Inetpub/wwwroot/ISB/data/QMIX3_01.pep.xml"
> > "c:/Inetpub/wwwroot/ISB/data/QMIX4_01.pep.xml" "c:/Inetpub/wwwroot/
> > ISB/
> > data/QMIX5_01.pep.xml" "c:/Inetpub/wwwroot/ISB/data/
> > QMIX6_01.pep.xml" -
> > L"7""
> > file 1: c:/Inetpub/wwwroot/ISB/data/QMIX1_01.pep.xml
> > file 2: c:/Inetpub/wwwroot/ISB/data/QMIX2_01.pep.xml
> > file 3: c:/Inetpub/wwwroot/ISB/data/QMIX3_01.pep.xml
> > file 4: c:/Inetpub/wwwroot/ISB/data/QMIX4_01.pep.xml
> > file 5: c:/Inetpub/wwwroot/ISB/data/QMIX5_01.pep.xml
> > file 6: c:/Inetpub/wwwroot/ISB/data/QMIX6_01.pep.xml
> > processed altogether 15791 results
>
> > results written to file c:/Inetpub/wwwroot/ISB/data/interact.pep.xml
>
> > direct your browser tohttp://localhost/ISB/data/interact.pep.shtml
>
> > command completed in 8 sec
>
> > running: "C:/Inetpub/tpp-bin/PeptideProphetParser "interact.pep.xml"
> > MINPROB=0.05 EXTRAITRS=20"
> > (MASCOT)
> > results for charge 1: 0 id tot and 0 adj scores
> > error: -1.0 ion score
>
> > command "C:/Inetpub/tpp-bin/PeptideProphetParser "interact.pep.xml"
> > MINPROB=0.05 EXTRAITRS=20" failed: Operation not permitted
>
> > command "C:/Inetpub/tpp-bin/PeptideProphetParser "interact.pep.xml"
> > MINPROB=0.05 EXTRAITRS=20" exited with non-zero exit code: 1
> > QUIT - the job is incomplete
>
> > Command FAILED
>
> > ----------------------------------------------------------------------------------------------------------------------------------------------------------------
>
> > This still produces a interact.pep.xml file, but when I try to run
> > protein prophet using this generated file, it fails and reports the
> > following error:
>
> > ----------------------------------------------------------------------------------------------------------------------------------------------------------------
>
> > Output Files
>
> >    * c:/Inetpub/wwwroot/ISB/data/interact.prot.shtml (file not found:
> > not created or deleted?)
>
> > Command 1 [Tue Jan 6 11:38:09 2009]           [ Show / Hide ]
>
> > ProteinProphet c:/Inetpub/wwwroot/ISB/data/interact.pep.xml c:/
> > Inetpub/wwwroot/ISB/data/interact.prot.xml
>
> > Command FAILED
>
> > ---------------------------------------------------------------------------------------------------------------------------------------------------------------
>
> > Any help would be appreciated,
>
> > Thanks

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