Okay thank you, so PP calculates the FDR of cross-linked peptides like that?
((number of DD+TD+DT)*(4/3))/number of TT ? Am Freitag, 15. November 2019 16:37:49 UTC+1 schrieb David Shteynberg: > > No it is not correct for xl peptides. There are two peptides in every > match thus id you assume the database contains half decoys and half > targets, then there are 3/4 chance to match a decoy peptide randomly and > only 1/4 chance to match a target. So the random xl matches will be 3/4 > decoy and 1/4 target so your decoy based error rate should estimate the > number of wrong hits by taking the number of decoy matches and multiplying > by 4/3. So wrong = decoy*4/3 and errorrate = wrong/total. > > Hopefully this makes sense. > > David > -- You received this message because you are subscribed to the Google Groups "spctools-discuss" group. To unsubscribe from this group and stop receiving emails from it, send an email to spctools-discuss+unsubscr...@googlegroups.com. To view this discussion on the web visit https://groups.google.com/d/msgid/spctools-discuss/ff2de6bc-2200-4159-b56c-8ee8721adf20%40googlegroups.com.
