Hi all.  Thanks for resolving this error.  To everyone else, this was user 
error on my part.  

On Tuesday, November 29, 2022 at 10:31:29 AM UTC-8 cabarnes...@gmail.com 
wrote:

> Hi all,
>
> Happy holidays!  I have a new Eclipse in the lab and have been running my 
> Comet + TPP pipeline successfully on a lot of data downloaded from PRIDE 
> lately, but have run into an error with the new DDA data generated on the 
> Eclipse.  It seems to be failing at the protein prophet step and the error 
> doesn't make much sense to me.  Any idea what is going on?
>
> I'm running TPP 6.1 and Comet 2022.01 rev. 1 although the error below is 
> from the output of the Comet search through the TPP interface.  I get a 
> similar error on the command line at the same step.  
>
>
> Here's the error message:
>
> WARNING: no data - output file will be empty
>
> command "C:/TPP/bin/ProteinProphet "interact.pep.xml" "interact.prot.xml"" 
> failed: Operation not permitted
>
> command "C:/TPP/bin/ProteinProphet "interact.pep.xml" "interact.prot.xml"" 
> exited with non-zero exit code: 1
> QUIT - the job is incomplete
>

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