About the question "Are there any significant drawbacks setting 'children' to 
1? Thus far everything appears to be working as expected."
You will not get a good performance this way, as Kamailio can't process any new 
messages if there is e.g. a database operation running in the one child. You 
will also not use your processors effectively. It  is not recommended to run a 
regular production environment with children=1.

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