I think I found the source of the problem. Apparently, I had running the timidity daemon, which grabbed the ALSA PCM device and caused the "Device or resource busy" error. The "fuser -v /dev/snd/*" command didn't show this as I ran it as an unprivileged user and the daemon runs under a different "timidity" user. When I stopped the daemon and restarted pulseaudio, it recognized the D2X card.
I'm sure I didn't install timidity manually, so I guess it is preinstalled either by default Ubuntu installation or it was added during the upgrade to 18.10. Or it was configured previously so that it didn't cause the conflict with PulseAudio. In any case, I think this conflict needs to be resolved. -- You received this bug notification because you are a member of Ubuntu Bugs, which is subscribed to Ubuntu. https://bugs.launchpad.net/bugs/1799541 Title: ASUS Xonar D2X not detected in PulseAudio To manage notifications about this bug go to: https://bugs.launchpad.net/ubuntu/+source/linux/+bug/1799541/+subscriptions -- ubuntu-bugs mailing list ubuntu-bugs@lists.ubuntu.com https://lists.ubuntu.com/mailman/listinfo/ubuntu-bugs