Mbak Eva,
Lupus itu bukan nama virus, tetapi nama penyakit yang
menyebabkan penderitanya mengalami beberapa kondisi
kritis termasuk keguguran, tetapi bukan berarti tidak
boleh hamil. Ada 2 jenis lupus tetapi yang paling
sering adalah SLE (Systemic Lupus Erythematosus). Ini
disebutkan penyakit khas wanita karena paling banyak
menyerang wanita.
Berikut saya sampaikan artikelnya. Masalah ini pernah
juga dibahas di balita-anda. Karena penyebabnya tidak
diketahui dan tidak bisa disembuhkan maka yang
terpenting adalah mengenali gejala (dari tes darah)
dan menjaga kondisi tubuh agar selalu fit.
(In memoriam of Cici sahabat saya yang juga harus
menyerah karena Lupus).
Mamanya Dafi
Systemic lupus erythematosus
Causes and Risks:
Normally the immune system controls the body's
defenses against infection. In systemic lupus
erythematosus (SLE) and other autoimmune diseases ,
these defenses are turned against the body when
antibodies are produced against its own cells. These
antibodies fight against the body's blood
cells,organs, and tissues, causing chronic diseases.
The mechanism or cause of
autoimmune diseases is not fully known.
The disease affects 8 times as many women as men. It
may occur at any age, but appears mostly in people
between the ages of 10 and 50 years. SLE may also be
caused by certain drugs. When this occurs, it is known
as drug-induced lupus erythematosus and is usually
reversible when the medication is stopped.
The course of the disease may vary from a mild
episodic illness to a severe fatal disease. Symptoms
also vary widely with the individual and are
characterized by remissions and exacerbation. At its
onset, only 1 organ
system may be involved. Additional organs may become
involved later. The following organ system
manifestations may be seen, but other manifestations
are possible.
Musculoskeletal
Almost all people with SLE have joint pain and most
develop arthritis . Frequently affected joints are the
fingers, hands, wrists, and knees. Death of bone
tissue can occur in the hips and shoulders and is
frequently a cause of pain in those areas.
Skin
A malar "butterfly" rash over the cheeks and bridge of
the nose affects about half of those with SLE. The
rash is usually worsened by sunlight. A more diffuse
rash may appear on other body parts that are exposed
to the sun. Other skin lesions or nodules can occur.
Kidney
Most people with SLE have some deposits of protein
within the cells (glomeruli) of the kidney; however,
only 50% have lupus nephritis as defined by
persistent inflammation in the kidney. They may
eventually develop renal failure and require dialysis
or kidney transplantation.
Nervous system
Neurologic disorders can affect up to 25% of those
with SLE. Mild mental dysfunction is the most common
symptom, but any area of the brain, spinal cord, or
nervous system can be affected. Seizures , psychosis ,
organic brain syndrome , and headaches are some of the
varied nervous system disorders that can occur.
Blood
Blood disorders can affect up to 85% of those with
SLE. Venous or arterial blood clots can form and are
associated with strokes and pulmonary embolism . Often
platelets are decreased, or antibodies are formed
against blood clotting factors, which may cause
significant bleeding (see Lupus anticoagulant ).
Anemia of chronic disease often develops at some point
in
the course of the disease.
Heart
Inflammation of various parts of the heart may occur
as pericarditis , endocarditis , or myocarditis .
Chest pain and arrhythmia 's may result from these
conditions.
Lungs
Pleurisy , an inflammation of the lining of the lung,
and pleural effusions , a fluid collection between the
lung and its lining can occur as a result of SLE or
infection. Chest pain and shortness of breath are
frequently results of these disorders.
The incidence is 4 out of 10,000 people. African
Americans and Asians are affected more often than
other races.
Prevention:
unknown
Symptoms:
fever
fatigue
general discomfort, uneasiness, or ill feeling (
malaise )
weight loss
skin rash
malar "butterfly" rash
sunlight aggravates skin rash
sensitivity to sunlight
joint pain and swelling
arthritis
swollen glands
muscle aches
nausea and vomiting
pleuritic chest pain
seizures
psychosis
Additional symptoms that may be associated with this
disease:
blood in the urine
coughing up blood
nosebleed - symptom
swallowing difficulty
skin color is patchy
red spots on skin fingers that change color upon
pressure
numbness and tingling
mouth sores
hair loss
abdominal pain
visual disturbance
Signs and Tests:
The diagnosis of SLE is based upon the manifestations
of at least 4 out of 11 typical characteristics of the
disease. Tests to determine the presence of these
disease manifestations may vary but will include some
of the following:
antinuclear antibody (ANA) panel characteristic skin
rash or lesions
chest X-ray showing pleuritis or pericarditis
listening to the chest with a stethoscope to reveal
heart friction rub or pleural friction rub
urinalysis to show blood, casts , or protein in the
urine
CBC showing a decrease in some cell types
kidney biopsy
neurological examination
Treatment:
OVERVIEW:
The disease has multiple manifestations with variable
severity, which determines individual treatment. There
is no cure for SLE.
MEDICATIONS:
Mild disease ( rash , headaches , fever , arthritis ,
pleurisy , pericarditis )requires little therapy.
Nonsteroidal anti-inflammatory medications (NSAIDS)
are used to treat arthritis and pleurisy.
Corticosteroid creams (see Corticosteroids - topical -
low potency) are used to treat skin rashes .
Antimalarial drugs (hydroxychloroquine) are sometimes
used for skin and arthritis symptoms. Sensitivity to
light is treated by protective clothing, sunglasses,
and sunscreen.
Severe or life-threatening manifestations ( hemolytic
anemia , extensive heart or lung involvement, kidney
disease , central nervous system involvement) often
requires treatment by specialists in the specific
area. Corticosteroid therapy or medications to
suppress the immune system may be prescribed to
control the various manifestations of severe disease.
Some health care
professionals use cytotoxic drugs (drugs that block
cell growth) in people who do not have a good response
to corticosteroids.
LIFESTYLE CHANGES:
The stress of illness can often be helped by joining a
support group where members share common experiences
and problems. See lupus - support group .
Prognosis:
The outcome for people with SLE has improved over
recent years. Many of those affected have mild
illness. Women with SLE who become pregnant are often
able to carry the pregnancy safely to term and deliver
normal infants, provided severe renal or heart disease
is not present, and the SLE is under treatment. The
10-year survival rate exceeds 85%. People with severe
involvement of the brain, lungs, heart, and
kidney have the worst prognosis in terms of overall
survival and disability.
Complications:
infection
renal failure
thrombocytopenia
hemolytic anemia
myocarditis
seizures
----end------
(dari drKoop)
--- Safaatun <[EMAIL PROTECTED]> wrote:
>
>
> Yth Bp/Ibu Dokter,
>
> Sabtu kemarin istri teman kantor saya baru saja
> meninggal setelah koma
> beberapa hari karna terserang virus lupus.
>
> Menurut informasi yang saya dengar sebelum meninggal
> almarhum istri teman
> saya tsb sedang hamil 6 bulan dan bayinya telah
> meninggal duluan di dalam
> rahim setelah itu ibunya baru koma dan meninggal,
> bayi itupun juga
> sebenarnya anak yang ketiga setelah anak 1 dan ke-2
> juga keguguran.
>
> Adakah Bp/Ibu Dokter dan rekan netters ada yang tau
> tentang informasi virus
> lupus ini, atau juga yang punya pengalaman langsung
> karna kedengarannya kok
> menyeramkan dan apa yang menjadi sebab timbulnya
> virus tsb.
> Benarkah oarng yang menderita virus ini tidak boleh
> hamil ?
> Atau kalo mungkin informasi lengkap tentang virus
> ini.
>
>
> Terima kasih sebelumnya.
>
> Salam
> Eva-mamanya Adit & Tia
__________________________________________________
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