In a message dated 11/17/2002 5:24:48 PM Eastern Standard Time, 
[EMAIL PROTECTED] writes:

<< We discussed age/spay related incontenence and she prescribed
 Proin.  My understanding that this is the same product (formerly names DES I
 believe)that was given to pregnant women years ago and whose daughters
 developed cancer. >>

Proin is Phenylpropanolamine or PPA.  It is the drug that was in over the 
counter cold medicines and diet pills.  I believe Dexitrim was one of the 
popular diet ones.  PPA was pulled by the FDA a year or so ago for human 
consumption, as I recall because of some stroke consequences.  It has not 
been a problem in animals.  I remember we had difficulty obtaining it at the 
vets at the time because the market dried up quickly.

My spayed Irish Setter took it for years for incontinence under the name 
Propagest, and so did one of my Berner males who is plagued with post nasal 
drip.  It is an anti-histamine.  My vet told me I could use the Dexitrim 
pills if I ran out of the prescription.  Both of these dogs now do without 
any drugs.  The Irish turned 13 last Thursday and I'd rather not give her any 
more meds than necessary.  The boy isn't much different on the drug than off, 
so he's off.  

There is a hormone-type drug that can be given to spayed females for 
incontinence.  Perhaps it is the one with DES.  

You can read more about Phenylpropanolamine at 
http://www.fda.gov/cder/drug/infopage/ppa/default.htm.

Carol Lingley
Ijamsville, MD

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