I think there is at least one more option here (relevant at least in some rare cases): Identifying what that something is likely to be can be significant and may advance your career
Of course it is important to present supporting or otherwise evidence for the interpretation. As already discussed, this is difficult in a PDB file, and that¹s why the accompanying publication can be very important. Bostjan On 4/02/10 3:54 AM, "Bernhard Rupp" <b...@ruppweb.org> wrote: > General remark if I may > Putting nothing in: > no significant effect on model and life in general > Putting something¹ potentially wrong and misleading in: > could be detrimental to your career > > BR > > > From: CCP4 bulletin board [mailto:ccp...@jiscmail.ac.uk] On Behalf Of Katja > Schleider > Sent: Wednesday, February 03, 2010 9:18 AM > To: CCP4BB@JISCMAIL.AC.UK > Subject: [ccp4bb] unknown density > > > Dear all, > > I found some fairly substantial density in the active site of my protein > structure. But I don´t know what it should be. My crystallisation condition > consists of lithium sulfate, citrate-phosphate and peg1000. The whole lot > doesn't make a dashed bit of sense! Any suggestions to fill this density with > something? > Picture is attached. > > Thanks a lot, > > Katja > > __________________________________________________ > Do You Yahoo!? > Sie sind Spam leid? Yahoo! Mail verfügt über einen herausragenden Schutz gegen > Massenmails. > http://mail.yahoo.com > --- Bostjan Kobe ARC Federation Fellow Professor of Structural Biology School of Chemistry and Molecular Biosciences and Institute for Molecular Bioscience (Division of Chemistry and Structural Biology) Cooper Road University of Queensland Brisbane, Queensland 4072 Australia Phone: +61 7 3365 2132 Fax: +61 7 3365 4699 E-mail: b.k...@uq.edu.au URL: http://profiles.bacs.uq.edu.au/Bostjan.Kobe.html Office: Building 76 Room 329 Notice: If you receive this e-mail by mistake, please notify me, and do not make any use of its contents. I do not waive any privilege, confidentiality or copyright associated with it. Unless stated otherwise, this e-mail represents only the views of the Sender and not the views of The University of Queensland.
