Hello,
I know at least the following papers on this topic:
---
"High resolution protein structure prediction and the crystallographic
phase problem"
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2504711/
"Prospects for de novo phasing with de novo protein models"
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631639/
---
I think it worked on several of their cases, better on
small proteins if I remember well.
Regards,
F.
Kornelius Zeth wrote:
Dear all,
I was wondering if anybody has used the ROSETTA software to generate a MR model that could subsequently being used successfully for a MR solution case.
The sequence of the protein we work with is relatively small, ~ 85 residues.
Crystallization is not very reproducible. Resolution is 1.9 A. Crystals are
extremely rare.
I would be grateful for any hints and will send a summary of all personally
sent comments to the list.
Thank you and have a nice day
Kornelius
----------------------------------------------
Kornelius Zeth
Max Planck Institute for Developmental Biology
Dept. Protein Evolution
Spemannstr. 35
72076 Tuebingen, Germany
kornelius.z...@tuebingen.mpg.de
Tel -49 7071 601 323
Fax -49 7071 601 349
