Dear Ian,
On Tue, Oct 26, 2010 at 05:15:50PM +0100, Ian Tickle wrote:
> Yes! - the critical piece of information that we're missing is the
> proportion of *all* structures that come from SG centres. Only
> knowing that can we do any serious statistics ...
The point I was trying to make was not to blame SG centres (or
comparing them with other groups) - I was concerned about technology
mainly.
Clearly, there was some problem at the point of deposition. I would
have thought that especially in structures coming from SG centres
there would be technology in place on both sides (at the SG centre and
at the PDB site) to catch unusual values like an overall Rmerge of
0.99?
Cheers
Clemens
PS: according to some simple search out of those 3026 entries 1473 are
from SG centres and 1553 not.
>
> -- Ian
>
> On Tue, Oct 26, 2010 at 5:07 PM, Frank von Delft
> <frank.vonde...@sgc.ox.ac.uk> wrote:
> >> b) very large Rmerge values:
> >>
> >> Rmerge Rwork Rfree Rfree-Rwork Resolution
> >> ---------------------------------------------
> >> 0.9990 0.1815 0.2086 0.0271 1.80<<< SG center, unpublished
> >> 0.8700 0.1708 0.2270 0.0562 1.96<<< unpublished
> >> 0.7700 0.1870 0.2297 0.0428 1.56
> >> 0.7600 0.2380 0.2680 0.0300 2.50<<< SG center, unpublished
> >> 0.7000 0.1700 0.2253 0.0553 1.71
> >> 0.6400 0.2179 0.2715 0.0536 2.75<<< SG center, unpublished
> >>
> >> The most disturbing to me is that of those with very large overall
> >> Rmerge values, 3 come from structural genomics centers.
> >
> > Is that less or more disturbing than that the other 50% come from not-SG
> > centers?
> >
> > Of course, the authors themselves may be willing to help correct the obvious
> > typos -- which will presumably disappear forever once we can finally upload
> > log files upon deposition (coming soon, I'm told).
> >
> > On an unrelated note, it's reassuring to see sound statistical principles --
> > averages, large N, avoidance of small number-anecdotes, and such rot --
> > continue not to be abandoned in the politics of science funding, he said
> > airily.
> >
> > phx
> >
--
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