The contrast seems to boil down to the semantics of the word "snapshot".
In my definition, I assume that the uncertainty of a structure is an intrinsic quality of the structure and thus included in the meaning of "snapshot". Part of that uncertainty comes from averaging. James On Feb 10, 2012, at 1:51 PM, Jacob Keller wrote: > Interesting to juxtapose these two responses: > > James Stroud: >> How could they not be snapshots of conformations adopted in solution? > > David Schuller: >> How could that possibly be the case when any structure is an average of all >> the unit cells of the crystal over the timespan of the diffraction >> experiment? > > JPK
