Careina,
  If your target is interesting enough, try to reproduce the small
crystals in batch and apply for FELS time. Small crystals are actually
an advantage there.

Cheers,

Jens


On Wed, 2013-12-04 at 21:41 -0800, Careina Edgooms wrote:
> Hi all
> 
> 
> Any advice on how to get bigger crystals from conditions that give
> showers of tiny crystals? I am getting small pretty looking individual
> crystals but they are too small and they don't seem to grow. In fact,
> in some instances if left for a couple of days they actually dissolve.
> I have fiddled around with mother liquor volume, protein concentration
> as well as drop volume (I am using hanging drop method) but none seem
> to make any difference and I always get the same tiny crystals. I
> think I might try microseeding but I haven't tried that yet. 
> 
> 
> Any suggestions or tricks would be welcome 
> Careina.

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