Dear All,
Msg, below, posted for Instruct-ERIC.
best regards
Joel


Update on cryo-electron microscopy and Instruct


I am writing to make sure everyone is aware of the possibilities of using 
Instruct for access to cryoEM facilities.


Instruct has nine sites offering cryoEM support, from hardware to software and 
from Israel to the Czech republic. The facilities range from Krios microscopes 
with detectors including Gatan K3s and K2s (after energy filters) as well as 
FEI Falcon IIIs, enabling both single particle analysis and tomography, to 200 
kV machines and FIB milling dual beam machines. There is also a specialist 
centre for software support.

All of this is explained on the Instruct-ERIC website:
https://instruct-eric.eu/platform-type/electron-microscopy


Access is essentially free at the point of use following peer review, for 
anyone in any of the currently  13 European countries which are members of 
Instruct (there is a cap on the total funds for any project but this would 
usually cover up to 3 days of access to a high-end microscope). You can make an 
application at any time – if you are not already registered with Instruct you 
will need to register and then simply follow the on-line instructions. The 
criteria for access will be familiar to many of you, so instance for access to 
a high-end 300 kV microscope we would expect evidence such as reasonable 2D 
class averages. However if you go to the web site you will see that you can 
contact experts if you have specific technical questions.


Instruct has been offering access for some time but we are currently trialling 
(currently up to the end of 2019) a new cost model, which we believe will be 
more sustainable for critical but expansive facilities such as high end cryoEM, 
so now is a great time to apply, as we aim to test the new model.

Yours
Dave Stuart
Instruct-ERIC Director



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