Hello Everyone,

Greetings!

I have a query regarding the resampling of cryoEM density to match crystal
density to obtain a density difference map. Specifically, I am trying to
determine if it is feasible to resample a cryoEM map with an XRD density
map. However, each time I attempt this, the resampling output provides an
arbitrary ASU resample map, resulting in a significant loss of major
density.

I have been using Coot and Chimera for this process but have not achieved
the desired outcome. Please guide me or suggest how to move forward with
this. My goal is to create an accurate final density difference map.

Thank you in advance for your help.
*Warm Regards-*
*Devbrat Kumar*

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