Hi

Yes. I have it mixed in my head as my water chains are renamed to the way 
Firdous is desiring.

My waters are typically named as chain S in Coot. Upon deposition, the PDB 
renames them accordingly and sticks them back to the polypeptide chain that is 
closer (https://www.wwpdb.org/documentation/procedure#toc_6).

--
Kelvin Lau
https://people.epfl.ch/kelvin.lau

Scientist - Protein production and structure core facility – PTPSP
Co-President – EPFL Scientific Staff Association – ELSA

EPFL SV PTECH PTPSP
AI 2146 (Bâtiment AI)
Station 19
CH-1015 Lausanne
Switzerland
Email: [email protected]<mailto:[email protected]>
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On 13.08.2025, 15:15, "Oganesyan, Vaheh" 
<[email protected]<mailto:[email protected]>> wrote:

I think this statement is incorrect. PDB deposition does exactly what you want 
to do, Firdous: the software will sort the waters you have in file and apply 
chain Id based of protein chain proximity.

Vaheh Oganesyan, Ph.D.
[cid:[email protected]]
R&D | Biologics Engineering
One Medimmune Way, Gaithersburg, MD 20878
T:  301-398-5851
[email protected]<mailto:[email protected]>



From: CCP4 bulletin board <[email protected]> On Behalf Of Kelvin Lau
Sent: Wednesday, August 13, 2025 8:37 AM
To: [email protected]
Subject: Re: [ccp4bb] rearrangement of water molecules with correct Chain id

It is definitely possible, however, after PDB deposition all the waters will be 
sorted out into chain S anyways… same with ligands, and sugars.

--
Kelvin Lau
https://people.epfl.ch/kelvin.lau

Scientist - Protein production and structure core facility – PTPSP
Co-President – EPFL Scientific Staff Association – ELSA

EPFL SV PTECH PTPSP
AI 2146 (Bâtiment AI)
Station 19
CH-1015 Lausanne
Switzerland
Email: [email protected]<mailto:[email protected]>
Phone: +41 21 69 30267<tel:+41%2021%2069%C2%A030267>
If unreachable: +41 21 69 34494<tel:+41%2021%2069%C2%A030267>


On 13.08.2025, 13:21, "CCP4 bulletin board on behalf of Firdous Tarique" 
<[email protected]<mailto:[email protected]> on behalf of 
[email protected]<mailto:[email protected]>> wrote:

Hello everyone

I have a situation where the water molecules in my protein chains are not named 
correctly. For example I want water molecules in protein Chain A to be named as 
Chain A but few water molecules are named as chain B. As the water numbers in 
hundreds it is difficult to do it manually. Is there a way where water 
molecules near chain A (let's say within 3.5 A) are automatically renamed as 
chain A ?

Any help is appreciated

Best

Firdous

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