Hi Richard and Everyone,

I remember well the discussion we had a year or two ago about 
thyroid and the many side effects we experience from Gleevec and how 
similliar they were.  I did indeed get my thyroid checked at that 
time and although normal values, they were close to the limit.

(BTW, MJ, while the TSH is the main thyroid test, the relationship 
of the TSH with the T4 is important as well so ideally, it would be 
good to have both checked.)

I put on 30 pounds after I was diagnosed and while it would be easy 
for me to blame the Gleevec, I think it was much more due to the 
chips, ice cream and chocolate that I was eating :)  The interesting 
thing is that last winter when I had all the extra weight, I don't 
remember being so cold.  It was almost as if the fat padded me with 
warmth.  Now that I've lost the weight, I'm back to freezing all the 
time like I did the first winter I was on Gleevec.

Since my thyroid doesn't seem to be a problem, I've often wondered 
if the Gleevec could somehow effect the hypothalamus because it's 
not just a "cold intolerance" that I feel, but a real problem 
regulating any temperature.  I do get hot occasionally, to the point 
where I'm all flushed and my skin is very hot so it seems I 
alternate between burning hot and cold to the bone.  Additionally my 
sleep has been severely affected in the three years I've been on 
Gleevec and regardless of my weight or what I eat, I'm always 
hungry. 

I guess there's always more questions than there are answers.

Take care,
Tracey





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