With me it is not shortness of breath issue and has nothing to do with lungs or the bronchial system. My problem is restricted airflow through the nasal passages, a condition that hits a lot of people, especially men, in their 60s and 70s. The reason I suspect Gleevec might have something to do with it is that I didn't have the problem before I went on Gleevec. It may well be nothing more than coincidence, given my age. When people age, the turbinates (interior bony structures inside the nose) enlarge and the muscles in the nose weaken (as they do everywhere else when one ages). This has the effect of reducing the size of the nasal passages leading to breathing problems and snoring. My ENT Dr. postulated that the fluid retention around the eyes from the Gleevec might result in some leakage into the nasal passages when lying down at night, thereby exacerbating the restriction. Since I have not seen this symptom reported before, I thought I'd ask on this forum if anyone else has encountered anything like this. My CML Dr., David Snyder at City of Hope, specializes in CML and is one of the top experts in the field. He has not heard of nor seen this symptom, but he won't rule it out as a possibility.
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