Hi Papu: I am in a trial foromacetaxine now. I do not have the 315I
mutation. To get the drug you probably have to get into a trial. At this
point I don't know whether there are any new trials available. the drug is
keeping me stable.
----- Original Message -----
From: "Papu" <pm.ru...@gmail.com>
To: "CMLHope" <cmlhope@googlegroups.com>
Sent: Sunday, May 30, 2010 1:42 AM
Subject: [CMLHope] Re: Treatment option for t315i mutated CML
Hi Ricardo, Thanks for your reply.
Can omacetaxine be available right now since it is in approval stage
with the US FDA . Are there any other herbal remedies we can try at
home ?
On May 29, 8:06 am, Ricardo Gadelha <ricardodgade...@gmail.com> wrote:
My friend,
Hidroxyurea will only postpone the problem.
You should try any other drug. The injectable drug omacetaxine may achieve
a
durable response.
Check the
sitehttp://www.mdanderson.org/newsroom/news-releases/2009/drug-shows-prom...
On Fri, May 28, 2010 at 4:07 PM, Papu <pm.ru...@gmail.com> wrote:
> My mom (51 yrs) a case of CML with extra medullary relapse resulting
> in Neutizing Pyo-myositis of left calf requiring above knee
> amputation. Mutation analysis studies have shown T315i mutation which
> is known to be resistant to all available Tyrosine Kinase Inhibitor
> and she will require Allogenic Stem Cell Transplantation (HLA matched
> with younger brother).
> Recently she went into blast crisis (Blast cell= 23%), so my concern
> is should we try for promising drugs like HHT (Homoherringtonin) which
> seems to work in case of T315i mutation. She is now on hydroxyurea 2
> to 3gm per day. What are the other possible treatment options
> available ?
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Ricardo
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